CGF胶原蛋白仿生膜性能比较及在口腔修复中的应用

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中图分类号：R783；TQ427.2+6 文献标志码：A文章编号：1001-5922（2025）12-0056-04

Abstract：Inorder toexplore therepair efectofCGFgel membrane inoral implant，this study evaluated the effects of different temperature conditions （ 25‰ and 4 ΔC ）on the properties of CGF gel membrane through in vitro experiments and clinicalcontroledtrials，anddiscussed itsappication effect inpromoting periodontal softandhard tissue regeneration and implant surgery.The in vitro test resultsshowed that the CGF gel film prepared at room temperature had better mechanical properties.The clinical study included 48 patients with severe periodontitis who needed to be implanted after tooth extraction.They were randomly divided into CGF group and control group.

Guided bone tissue regeneration surgery was performedand implant surgery was performed at 6 months after surgery.Theresults showed that the wound healing time of the CGF group was shorter and the pain relief was better. The initial stabilityof the implant intheCGF group was beter and the bonedensitywassignificantlyhigher than that in the control group.This study confirmed that CGF membrane can reduce postoperative reaction，accelerate tissue repair and promote bone regeneration through multiple mechanisms.It provides a reliable biological material selection for guided bone regeneration surgery and oral implant surgery，and has important clinical application value.

Key words：concentrated growth factor;guided bone regeneration;oral implant

随着口腔种植技术的迅速发展，引导骨再生已成为解决骨缺损问题的关键手段[1-2]。（剩余3733字）