色谱-质谱联用技术在农药残留检测中的应用及优化策略

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Application and Optimization Strategies of ChromatographyMass Spectrometry in Pesticide Residue Detection

CHEN Huagui （Yuexi County Food and Drug Inspection and Testing Center， Yuexi 616650， China）

Abstract： Pesticide residues may have serious impacts on human health，environmental protection and industrial development. This paper briefly summarizes the application overview of chromatography-mass spectrometry technology in pesticide residue detection，and analyzes the main problems existing in its application，including the low efciency of simultaneous extraction of multiple residues，the low sensitivity of low-concentration trace detection，andtheeasy occurrence offalse positive/falsenegativeresults，and proposes optimizationstrategies such as optimizing sample pretreatment methods，optimizing chromatographic separation conditions，strengthening personnel training，and implementingcoldchain transportationand storageofsamples，with theaimof improvingthe technical system of pesticide residue detection and enhancing the efficiency of food safety supervision.

Keywords： chromatography-mass spectrometry technology; pesticide residue detection; simultaneous extraction of multiple residues

随着经济的发展和社会的进步，人们对食品安全的重视程度日益提高，使得农药残留问题成为公众关注的焦点。（剩余3785字）