DOHaD理念导向的膳食治疗及自我调节对血透合并失眠患者睡眠的影响

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The Influence of Dietary Intervention Guided by the Developmental Origins of Health and Disease（DOHaD and Self-rsegulation Intervention on Sleep in Patients with Hemodialysis and Insomnia

LIN Yapeng，CHENG Xiaojuan，WU Yumiao，SU Meiling （Xiamen Fifth Hospital，Xiamen 36li01，China）

AbstractObjective：Toanalyzethevalueof dietaryintervention guidedbythe DOHaDcombined withself-regulationinterventioninmprovingsleepqualityforhemodialysispatients with insomnia.Methods：Atotalof 8Opatientswhohadstablehemodialysis with isomniaadmitedinthe hospitalfrom January 2O22 to December 2O23were selectedastheresearch subjectsandrandomlydivided intoacontrolgroupandanobservation group with4Ocasesineachgroup.Thecontrol groupreceivedroutinecare andtheobservationgroupreceivedtheDOHaD-guideddietaryinterventioandself-regulationintervention.Theoverallsleepquality，salivarycortisoloncenatioumbrofpatietstakingsepngpilsurativeateofseepsodersndiideneofoor sleepbeforeandaftertheintervention werecompared.Results：There wasno statisticallysignificantdiferenceintheindicators before intervention between the two groups（ P>0.05 ）. However，after the intervention，the observation group had beter overall sleepqualitylowersaivaryortisolconcentratin，fewerpatientstakingslepingpils，highercurerateofsleepdisodes，ndlower incidence of poor sleep，with statistically significant differences （ P<0.05 ）. Conclusion ： Dietary intervention guided by the DOHaDcanimproveslepqualitybysuplyingesential nutrients，providingreasonable timetableformeals，andadjustingdietary habitstomaintainnormalbrainandbodyfunctionsforhemodialysispatientswithinsomnia.Self-regulationinterventioncanhelp patientsbuildalong-termsablesephabits，enhanceslepqualityndkeeptebodyintealenvironmentstable，furthrproiding a better physical condition for hemodialysis.

KeywordsDOHaDguided；Dietary intervention；Self-regulated intervention；Hemodialysispatientswith insomnia；Sleep；Hemodialysis；Developmental origins of health and disease； Self-regulating intervention

中图分类号：R338.63 文献标识码：A doi：10.3969/j. issn.2095-7130.2025.07.035

血透患者的睡眠质量受多方面因素干扰，包含有精神因素、心理因素、血透次数、年龄、透析时间以及肾小球滤过率下降等一系列因素[1]。（剩余5506字）