蔗糖水联合非营养性吸吮对新生儿操作性 疼痛的缓解及睡眠的影响

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The Effect of Sucrose Water Combined with Non-nutritive Sucking ontheReliefofProceduralPainandSleepinNewborns

LI Xinting

（Department of Neonatology，Honghuagang District People's Hospital，Guizhou ，Zunyi 56300o，China）

AbstractObjective：Toevaluatetheefectof sucrose watercombinedwithnon-nutritivesuckinginalleviating procedural pain andimprovingslepqualityinnewborns.Methods;FromJanuary2O2O to January2025，atotalof12Onewbornsadmited tothe DepartmentofNeonatologyofour hospital were included inthe studyandrandomlydivided intoanobservationgroup（6O cases） andacontrol group（6Ocases）byarandom number table.Thecontrol groupreceived sucrose waterfeeding toallviate procedural painwhiletheobservation groupreceivedsucrose watercombined with non-nutritivesucking.Thepain interventionefects during the procedure were compared using the Neonatal Infant Pain Scale（NIPS）and crying parameters（crying rate，crying duration）. Thephysiological indicators（heartaterespiratoryrate，bloodoxygensaturation）bforeandduringtheoperation，aswellassleep qualityparameterswithin5daysaftertheoperation（including totaldailysleeptime，nightimesleepduration，numberofnightie awakenings，total dailyawakening duration，proportionofactiveslee（AS），quietslep（QS）time，frequencyof abnormal sleep movements）ofthetwogroupsofpatients werecompared.Results：During theoperation，theNISscores，cryingrates，cryingduration，heartrateandrespiratoryrateoftheobservationgroupweresignificantlylowerthanthoseofthecontrolgroup，whileeblood oxygen saturation was significantly higher than that of the control group（ P<0.05 ）. Within 5 days after the operation，the average totaldailysleeptimeandnightimeslpdurationoftheobservationgroupweresignificantlyhigherthanthoseofthecontrol group，and the number of nightime awakenings was significantly lower than that of the control group（ P<0.05 ）. Conclusion ： The combinationofsucrosewaterandnon-nutritivesuckingisefectiveinrelieving proceduralpaininnewbors.Itsignificantlylleviates pain，promotes greater physiological stability，and effectively improves sleepquality after the procedure.

KeywordsNeonatal proceduralpain；Sucrose water;Non-nutritive sucking；Sleepquality； Heartrate;；Sleep duration；Number of nighttime awakenings； Abnormal sleep movements

中图分类号：R338.63 文献标识码：A doi：10.3969/j. issn.2095-7130.2025.07.007

新生儿操作性疼痛会引发应激反应，并通过激活下丘脑-垂体-肾上腺轴，促使皮质醇释放节律紊乱，直接抑制松果体褪黑素合成，导致昼夜节律相位偏移1。（剩余4543字）