血清PCT在脓毒症诊断标准由Sepsis-1变为Sepsis-3时诊断效能的差异分析

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Difference Analysis of Diagnostic Efficiency of Serum PCT When the Diagnostic Criteria of Sepsis Change from Sepsis-1 to Sepsis-3

ZHUFeifei KANG Rui* （ShanghaiJiadingHospitalofTraditional Chinese Medicine）

Abstract： Objective： To investigate the difference of diagnostic efcacyof serum procaleitonin （PCT） insepsis when the diagnostic criteria change from Sepsis-1 to Sepsis-3.Methods： Atotalof195 patients with infection or/and systemic inflammatory response syndrome （SIRS）admited to Shanghai Jiading Hospital of Traditional Chinese Medicine from February 2022 to August 2024 were selected for diagnosis with Sepsis-1 and Sepsis-3 respectively，and thevalueof PCTin diagnosing sepsis and sepsis shock under diferent criteria was compared.Results： The PCTdetection value ofsepsis shock patientsunder Sepsis-1and Sepsis-3criteria was higher thanthat ofnon-sepsis patients，and the PCT detection value of sepsis patients was higher than that of non-sepsis patients （P<0.05） .TheAUC，sensitivityandJorden index of PCTwith Sepsis-1 were higherthanthosewith Sepsis-3.The sensitivity，specifcityandJorden index of PCT in the diagnosis of septic shock were similar under different diagnostic criteria. Conclusion： When the PCTchanges fromSepsis-1 to Sepsis-3，thediagnostic efficacyof sepsis is decreased，butthere isno significant change inthe diagnostic efficacy of sepsis shock.

Keywords：sepsis;procalcitonin;Sepsis-1 criteria;Sepsis-3 criteria

0 引言

脓毒症是由烧/创伤、感染、休克等所致，多伴组织继发性损伤，若不及时治疗，可致患者出现脓毒症休克，甚至死亡]。（剩余2823字）