白藜芦醇－玉米醇溶蛋白-果胶复合纳米颗粒的制备、表征与生物活性探究

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Abstract： This study aims to effectively encapsulate and deliver the functional bioactive compound resveratrol using acomposite nanoparticle system composed of zein and pectin as dual cariers.Nanocarrers were prepared with varying massoncentrationsofpectinandtheirparticlesize，polydispersityindex （PD），Zeta potential，encapslation effciency，loadingcapacity，photo/thermal stabilityandreleasebehaviorundersimulatedgastrontestinalconditions were systematically investigated. Experimental results showed that the incorporation of pectin significantly enhanced the stability and encapsulation efciency of resveratrol-loaded nanoparticles.When the mass ratio of zein to pectin was 100：35 ，the encapsulation efficiency and loading capacity reached their maximum values of （204号 83.89% and 15.25% ，respectively. In addition， the composite nanoparticles exhibited excellent protective effects on resveratrolwhen exposed to lightandheat，and demonstratedasustained and controlled release profile insimulated gastrointestinal environments.

Keywords： resveratrol; zein; pectin; nanoparticles

白藜芦醇是一种广泛存在于自然界植物中的多酚类化合物，因具有抗衰老、抗氧化、抗炎、心血管保护和抗肿瘤等多种有益健康的功效而受到广泛关注[1-2]。（剩余7036字）