CNKIAI在药物化学教学中的应用实践

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中图分类号：G642 文献标志码：A 文章编号：2096-000X（2026）03-0114-04

DOI：10.19980/j.CN23-1593/G4.2026.03.028

Abstract：Medicinalchemistryisadisciplinethatstudiestheconformationalrelationshipandsynthesismethodsofdrugs. Duetothecomplexandabstractcontentofthecourse，thetraditionalteachingmethodistoosimplistic，makingitdificultfor studentstofullygraspandapplytheknowledge.Theintroductionanddevelopmentofartificialinteligencetechnologyhas providednew waystoexpandteaching methodsandimprovestudentlearning.CNKIAIforAcademicisthelatestAI-assisted researchtoldevelopedbyChinaNationalKnowledgeInfrastructureintheraofartfialintellgence，designedtoservethe entirescientificresearchprocessByincorporatingCNKIAIintotheteachingofMedicinalchemistryandexploringnewteaching methods，wecanenhancetheeffciencyofteachers'instructionandstudents‘learning.Inthispaper，wetakeibuprofen，a commonlyused NSAID，asanexample.Byguiding students tofind，analyze，anddesignthesyntheticrouteof ibuprofenusing CNKIAIforAcademic，weaimtodeepenstudentsunderstandingandmasteryofthesubjectmater，improvetheirabilityto applykowlede，enhancetheirresearchskils，broadentheirprspectiveonthefrontiersofMedicinalchemistry，andultiately enhance thequaityof medicinalchemistryteaching.Thepurposeof thispaperistomakeusefulatemptsatapplying AI technology in Medicinal chemistry course of pharmaceutical engineering.

Keywords： CNKI;AI; medicinal chemistry；teaching methods; pharmaceutical engineering

药物化学课程是药学和制药工程等相关专业重要的专业课程，是一门发现与发明新药、合成化学药物、阐明药物化学性质、研究药物分子与机体细胞（生物大分子）之间相互作用规律的综合性学科。（剩余5390字）