附子（临江片）配方颗粒标准研究和应用思考
Research and Application Consideration on the Standard of Radix Aconiti Lateralis （Linjiang Slices） Formula Granules
LU Fang1.2 XU Xin1. 2 GAN Jiapan1.2 JIN Hongli1. 2.3* （1.GanjiangChinese Medicine InovationCenter;2.Jiangxi Provincial KeyLaboratory forPharmacodynamic Material Basis of Traditional Chinese Medicine; 3.Dalian Institute ofChemical Physics， Chinese Academy of Sciences）
Abstract：Radix Aconiti Lateralis is acommonlyused toxic traditional Chinese medicine inclinical practice. Radix Aconiti Lateralis （Linjiang Slices）is arepresentative variety that fullyutilizes the processing technologyof "Zhangbang”in Jiangxi.Through the methodof“processing with gingerandrice water，and steaming foralong time”， it achieves the goalof increasing eficiencyand reducing toxicity，ensuring good clinical drug safety. However，the current research onthe processng mechanism and pharmacological action ofRadix Aconiti Lateralis （Linjiang Slices） is far fromsufficient，and thereisalackoflocal qualitystandards，which seriously limits its clinical application.In ordertoprotectandinherittraditionalprocessng techniques inJiangxi，thisarticlesuggests takingformulagranules as a breakthrough point，strengthening the quality standardization research of Radix Aconiti Lateralis （Linjiang Slices） formula granules，clarifying the scientificconnotationofthe“Zhangbang"processng technology forincreasing efciency andreducing toxicity，breaking through the key technical botleneck of Radix AconitiLateralis （LinjiangSlices） formula granules industrialization，flling the research gapof local quality standards，and providing reference and demonstrationforthe research and applicationofquality standards for toxic traditional Chinese medicine formula granules.Atpresent，there are no reports on theresearch related to Radix Aconiti Lateralis （Linjiang Slices）formula granules， so this article has a certain degree of novelty.
Keywords：Radix AconitiLateralis （Linjiang Slices）; processing techniquesof“Zhangbang”;toxic traditional Chinese medicine; formula granules; local quality standards
0 引言
1附子（临江片）的炮制机理初探
附子为毛茛科植物乌头（AconitumcarmichaeliiDebx.）的子根的加工品，始载于《神农本草经》，其辛、甘，大热、有毒，具回阳救逆、补火助阳、散寒止痛的功效，用于亡阳虚脱及阳虚诸证。（剩余4805字）
