观察无创呼吸机治疗阻塞性睡眠呼吸 暂停低通气综合征疗效

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AbstractObjective：Toexploretheclinicaleficacyof non-invasiveventilators inthetreatmentofobstructivesleepapnea-hypopnea sydrome（OSAHS）.Methods：Atotal of119 patients diagnosed with OSAHSandtreatedatYuxi People's Hospital from January 2021 to April2O25were selectedas the study subjects.They were randomlydivided intoa control group（ n=74 ）and an observation group（ n=45 ）using a random number table method. The control group received health education，exercise promotion， weightloss，andactivepreventionandtreatmentofcomplications.Theobservationgroupreceivednon-invasiveventlationtreat ment with a ventilator in addition to the control group for more than 3 months.Nocturnal minimum oxygen saturation（ SaO2 ），apnea-hypopeaindex（AHI），and polysomnography（PSG）valuesof patients wererecorded beforeandafter treatmentResults：After intervention，bothgroupsofpatientsshowedadecreaseinAHIlevelsandtheobservationgroupwassignificantlylowerthanthe control group. The difference between the two groups was statistically significant （ P<0.05 ）.After intervention，minimum SaO2 （20 levelsinbothgroupsofpatientsicreased，withtheobservationgroupwassignificantlyhigherthanthecontrolgroup.Tediference between the two groups was statistically significant（ P<0.05 ）. The total effctive rate of treatment in the observation group wassignificantlyhigherthanthatinthecontrolgroup，andthedferencebetweenthetwogroupswasstatisticallsigificant（ P< 0.05）.Conclusion;Forpatients with OSAHS，theuseof non-invasiveventilatorsforlong-termtreatmenthassignificantherapeutic effects.This treatment method has high clinical application valueand is worthyofclinical promotionandapplication.

KeywordsObstructive sleep apnea hypopnea syndrome；Non-invasive ventilator；Continuous positive airway pressure ventilaon；Polysomnography；Disease grading；Effective treatment rate； Long-term treatment；Efficacy

中图分类号：R338.63；R364.4 文献标识码：A doi：10.3969/j. issn. 2095 -7130.2025.08.014

阻塞性睡眠呼吸暂停低通气综合征（Obstructive 害严重的源头性疾病，与多种疾病关联密切，显著增Sleep Apnea Hypopnea Syndrome，OSAHS）是一种危 加了高血压、冠心病、糖尿病等多种心脑血管疾病的

发病风险[1]，病情严重者甚至可能导致夜间猝死。（剩余4182字）