心理行为疗法联合哌罗匹隆对围绝经期失眠患者睡眠质量及不良情绪的影响

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AbstractObjective：Toexploretheefectof psychologicalbehavioral therapycombined with perospironeonsleequalityand negativeemotionsinmenopausalinsomniapatients.Methods：Atotalof88patientswithmenopausal insomniawhovisitedthe JiangningDistrict MaternalandChildHealthandFamilyPlanning Centerfrom January2O21toDecember 2023wereselected.Theywererandomlydividedintotwo groupsusingarandomnumbertable method，with44 patients ineach group.Patients in both groups were medicated with perospirone，andthoseintheoservationgroupwereaditionalltreatedwith psychological behavioraltherapy.Treatment wasperformedfor6weeks.Sleepquality（Pitsburgh SleepQualityIndex，PSQI），negativeemotions （Self-Rating AnxietyScale，SAS），（Self-Rating Depresion Scale，SDS），ndsex hormones（follcle stimulating hormone，SH）， （luteinizing hormone，LH）werecompared between groups.Results：PSQI，SASand SDSscores，SHandLH weresignificantly reduced in both groups，which were significantly lower in the observation group than the control group（l P<0.05 ） . Conclusion：Psychological behavioral therapycombined with perospironecan helpimprove the negativeemotionsofmenopausalinsomnia patients ，regulate hormone levels，and enhance sleep quality.

KeyWordsMenopausal; Insomnia;；Psychological behavioral therapy;； Perospirone； Sleepquality；Emotion;Sex hormone

中图分类号：R271.116;R256.23 文献标识码：A doi：10.3969/j.issn.2095-7130.2025.05.054

失眠是围绝经期人群常见的症状之一，主要是女性在绝经期后，卵巢功能衰退，雌激素水平下降，导致内分泌和自主神经系统功能紊乱，从而引起的一系列生理及心理变化[1-]。（剩余5602字）