中医电针疗法联合百乐眠胶囊对脑梗死后失眠患者睡眠质量的影响

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关键词中医电针疗法;百乐眠胶囊;脑梗死;失眠;匹兹堡睡眠质量指数;神经递质因子;焦虑;抑郁;针灸

AbstractObjective：Toanalyzetheefectof raditional Chinese medicineelectroacupuncturecombinedwithBailemianCapsules onsleepqualityininsomniapatientsaftererebralinfarction.Methods：Atotalof6Opatientswithpost-strokeinsomniaaditte to Tongliao People's Hospital from January2O24 to March 2O25 were selected as theresearch subjects.They were divided intoa controlgroupandanobservationgroupusingarandomnumber table method，with3Opatients ineach group.Thecontrolgroupreceived Bailemian Capsulesalone，whiletheobservationgroupreceivedaditionalTCMelectroacupuncture therapy.ThePisurgh SleepQualityIndex（PSQI）wasused tocompare thediferences insleepquality between twogroups.The Self-Rating Anxiety Scale（SAS）and Self-Rating Depression Scale（SDS）were used to compare the improvementof anxiety and depression symptoms.Neurotransmitter levels—including interleukin 1β （IL- 1β ），neuron-specific enolase（NSE），and 5-hydroxytryptamine（5- HT）—were measured viaenzyme-linkedimmunosorbent assay（ELISA）.Clinical eficacyrates were alsocompared.Results：After intervention，theSQIscore，SASscore，ndSDscoreofbthgroupsofpatientsdecreased，andtheobservationgroupwasigificantly lower than the control group. The diference between the two groups was statistically significant（ P<0.05 ）；Levels of IL1β andNSE decreased in both groups，while5-HT levels increased.The observation group exhibited significantlylower IL- 1β and NSElevelsandhigher5-HTlevelsthanthecontrol group.Thediferences between thetwo groupswere statisticallysignificant （ P<0.05 ）.Conclusion：For insomniapatientsafter cerebral infarction，thecombinationofTCM electroacupuncture and BailemianCapsulesfectivelyimprovesneurotransmiterlevels，alleviatesnegativeemotions，ndenhancessleepquality.Thsapproach demonstrates significant efficacy and is worthy of clinical promotion.

KeywordsTraditional Chinese Medicine Electroacupuncture Therapy；Bailemian Capsules；Cerebral infarction；Insomnia;Pittsburgh Sleep Quality Index； Neurotransmitter factors；Anxiety；Depression； Acupuncture and moxibustion

中图分类号：R743.34;R338.63 文献标识码：A doi：10.3969/j. issn.2095-7130.2025.05.019

脑卒中后出现的睡眠障碍是该疾病常见的并发 遭受失眠的困扰[1]。（剩余6507字）