心率变异性对阻塞性睡眠呼吸暂停患者心血管疾病的诊断价值

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AbstractObjective：Toexplorethefeasibilityofheartratevariability（HRV）indicators inasistig inthediagnosisofcardio vascular diseaseamong patients withobstructive sleepapnea-hypopnea syndrome（OSAS）.Methods：Atotalof12Opatients presentedwithsnoringandtreatedinthe DepartmentofOtolaryngology，SecondPeople HospitalofShanxi ProvincefromJanuary 2022 toApril2O24werecolected.Theyunderwent dynamicelectrocardiogram examinationat thesametimeandwereclssified into simple snoring group（ n=34 ），mild OSAS group（ n=30 ），moderate OSAS group（ n=33 ） and severe OSAS group（ n=23 ） according to thedegreeofOSAScalculatedbytheapnea hypopnea index（AHI）.HRVdataandarhythmiadata werecomparedamongthe four groups.Results：The standarddeviationof NNintervals（SDNN）andthe standard deviationof theaverage normalto-normal RR intervals（SDANN） every 5min in the simple snoring group were significantly higher than the mild，moderate and severe OSAS groups，while the low frequency（LF） was significantly shorter（ P<0.05 ）. SDNN，SDANN and high frequency（HF） were significantlylowerinthesevere OSAS groupthanthe mildand moderateOSASgroups，whileLFwassignificantlyhigher （ P<0.05 ）.The incidence of arhythmia was significantly higher in the severe OSAS group than the simple snoring group and mild and moderate OSAS groups （ P<0.05 ）. Conclusion：HRV indicators are highly feasible for assisting in the diagnosis of cardiovascular disease in OSAS patients，and can be used clinically according to the situation.

KeywordsHeart rate variability;Obstructive sleep apnea hypopnea syndrome; Cardiovascular disease;Diagnostic value

中图分类号：R699;R472.3 文献标识码：A doi：10.3969/j. issn.2095 -7130.2025.05.003

阻塞性睡眠呼吸暂停低通气综合征（ObstructiveSleepApneaSyndrom，OSAS）的发病机制与上呼吸道阻塞密切相关，相关研究显示[1]，OSAS是心脑血管疾病的高危因素，因此临床需要重视OSAS诊断和治疗。（剩余6771字）