食品添加剂在特殊人群中的安全性评估

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Safety Assessment of Food Additives in Special Populations

WEI Pingxia

（Lanzhou Petrochemical University of Vocational Technology， Lanzhou 73o207， China）

Abstract： This paper evaluates the health risks of aspartame in pregnant women， infants，phenylketonuria （PKU） patients and patients with chronic diseases，analyzes the diferences inthe methodologies ofcarcinogenicity assessment in international institutions，proposes a hierarchical threshold management system based onmetabolic Vulnerability，and suggests strengthening waring signs，accurate monitoring and dynamic risk communication.This studycan provide a scientific basis for the revision offood additive safety standards for special populations，and then promote a diferentiated risk management framework， which has important practical value for improving the global regulatory system and protecting the health of sensitive groups.

Keywords： food additives; special population; safety assessment

2023年7月，世界卫生组织（WorldHealthOrganization，WHO）下属国际癌症研究机构（International AgencyforResearchon Cancer，IARC）将阿斯巴甜（Aspartame）列为2B类可能致癌物（对人类致癌性证据有限），与其在180多个国家、6000余种食品饮料中的广泛使用形成鲜明对比。（剩余4952字）