小柴胡汤加味对胆结石微创保胆取石术患者疗效的影响

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[Abstract] Objective： To investigate the efect of modified Xiaochaihu Decoction on efficacy in patients undergoing minimally invasive galladder-preserving lithotomy for gallstones.Method： A total of 8O patients with galstonesadmitted tothe from October 2O22 to July 2O24 were divided into the control group （ n =40） and the combined group （n=4O） according to the random number table method.All patients underwent minimally invasive galblade-preserving lithotomy.The control group received postoperative routine treatment，whilethe combined group was given modified Xiaochaihu Decoction as adjuvant therapy on the basis of the control group.The clinical eficacy，stone removal rate，liver and gallbladder functionand gastrointestinal function of the two groups were compared，and the occurrence of adverse reactions was statistically analyzed. Result： The total effective rate of the combined group was higher than that of the control group （ P <0.05）. The stone removal rate of the combined group was 95.00% ，slightlyhigher than that of the control group （87.50% ），butthere was no statistically significant difference between the two groups （ P >0.05）. Compared with before treatment， the levels of TBIL，TCand total bileacid （TBA） inboth groupsdecreased significantlyafter 3monthsof treatment，and the above indicators in the combined group were lower than those in the control group （ P <0.05）. Compared with before treatment，the levels of serum gastrin （GAS）and somatostatin （SS） in both groups decreased significantly after3 monthsof treatment，whilethe levelof serum motilin （MTL） increased significantly，the improvementof the above indicators in the combined group were more obvious than those in the control group （ P <0.05）. There was no statistically significant diffrence in the total incidence of adverse reactions between the two groups （ P >0.05）.Conclusion： Modified Xiaochaihu Decoction demonstrates significant therapeutic efect on patients undergoing minimally invasive galbladder-preserving lithotomy for gallstones.It can help to improve liverand galbladder function， and gastrointestinal function， with good safety.

[KeyWords] Gallstone Modified Xiaochaihu Decoction Minimally invasive gallbladder-preserving lithotomyStone removal rate

First-author's address： Surgery Department1， ， 344000， China

doi：10.3969/j.issn.1674-4985.2025.31.014

胆结石作为临床消化系统常见疾病，主要表现为胆绞痛等，部分患者伴有背部放射痛，易与胃部疾病造成混淆，其发病因素包括不良饮食习惯、细菌及寄生虫感染等，对患者生命健康造成严重影响[1-2]。（剩余6062字）