HFNC与重组人脑利钠肽治疗急性心力衰竭的效果分析

打开文本图片集

[Abstract] Objective： To explore the therapeutic efect of nasal high flow nasal cannula oxygen therapy （HFNC） combined with Recombinant Human Brain Natriuretic Peptide （Xinhuosu） in patients with acute heart failure（AHF）and its influence oncardiac function and ventilationstatus of patients.Method：A totalof79 patients withAHFwho were admittedto Jinjiang Anhai HospitalfromJanuary 2O2OtoJuly2O22 were selected.Thepatients were divided into the control group （HFNC， n=38 ） and the observation group （HFNC + Xinhuosu， n=41 ）by random number table method.The clinical eficacy，ventilation status，cardiac function and qualityof life of thetwo groups were compared.Result： The total effctive rate of the observation group was higherthan thatof the control group （ P <0.05）.After treatment，the levels of PaCO ，left ventricular end-diastolic diameter （LVEDD），and left ventricular end-systolic diameter （LVESD）in the observation group were lower than those in the control group， while thelevelsof Pa02 ， Sa02 ，left ventricular ejection fraction （LVEF），and cardiac index（CI） were higher than those in the control group （ P <0.05）.After treatment， the Minnesota living with heart failure questionnaires （MLHFQ） score of the observation group was lower than that of the control group （ P <0.05）. Conclusion： HFNC combined with Xinhuosu inthe treatmentof AHFcan promote therecoveryof exchange heart function，improve ventilation function， enhance therapeutic effect and improve prognosis.

[Keywords]Acute heart failureHigh flow nasal cannula oxygen therapy Recombinant Human Brain Natriuretic Peptide Cardiac functionVentilatory status

First-author'saddress： Department of Critical Care Medicine，Jinjiang Anhai Hospital， Jinjiang 362261， China

doi：10.3969/j.issn.1674-4985.2025.31.012

急性心力衰竭（AHF）在急诊中属于常见病之一，主要指由急性心功能损伤，导致心脏排血量大幅减少，出现血液灌注不足的急性淤血综合征，其中在临床上左心心力衰竭更为常见[。（剩余5654字）