麦角新碱、卡贝缩宫素联合氨甲环酸在剖宫产产后出血患者中的应用效果

打开文本图片集

ApplicationEffectofErgometrineand CarbetocinCombined with Tranexamic Acid inPatientswith Postpartum Hemorrhage after Cesarean Section/HUANG Xiufang.//Medical Innovationof China，2025， 22（30）： 059-063

[Abstract]Objective：To investigate the efectof Ergometrine and Carbetocincombined with Tranexamic Acid on coagulation function in patients with postpartum hemorrhage （PPH） after cesarean section. Method： A totalof 93 patients with PPH after cesareansectionadmited to Leping Maternal and Child Health Hospital were included.The time period was from December 2O22 to December 2O24.They were divided into the control group n=47 ）and the observation group by the random number table method. The control group was treated with Ergometrine + Carbetocin，and the observation group was treated with Ergometrine + Carbetocin + Tranexamic Acid. The recovery-related indicators of the two groups were compared.Thecoagulation function indicators of the two groups were compared before treatment and 24 hours after treatment，and the occurrence of adverse reactions was recorded.Result： Compared withthecontrol group，the hemostasis time of theobservation group was shorterand the first time to get out of bed was earlier （ P <0.05）.24 hours after treatment，FIB increased，PT and APTT shortened， and D-Ddecreased in the two groups，and the changes in the observation group were more obvious than those in the control group （ P <0.05）.There was no statistically significant diffrence in the incidence of adverse reactions between the two groups （ P >0.05）.Conclusion： The combination of Ergometrine， Carbetocin and Tranexamic Acid in patients with PPH after cesarean section can improve coagulation function，shorten hemostasis time and promote patients to get out of bed as soon as possible.

[KeyWords] Cesarean sectionPostpartum hemorrhageErgometrineTranexamic Acid Coagulation function

First-author'saddress：DepartmentofGynecologyandObstetrics，LepingMaternaland ChildHealth Hospital，eping33314，Cna doi： 10.3969/j.issn.1674-4985.2025.30.015

产后出血（PPH）是产科常见分娩并发症，主要表现为产后出现阴道流血，若出血控制不及时，会导致失血性休克、严重贫血等并发症，甚至危及产妇生命安全。（剩余5110字）