弧菌噬菌体裂解酶和解聚酶的研究进展

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关键词：噬菌体；裂解酶；解聚酶；弧菌（Vibrio sp.）中图分类号：Q939.48 文献标识码：A文章编号：0439-8114（2025）08-0183-06DOI：10.14088/j.cnki.issn0439-8114.2025.08.028开放科学（资源服务）标识码（OSID）：

Research progress on Vibrio bacteriophage endolysin and depolymerase

HANWen-xin ⋅1 ，YANGRui-bing²，SUNXiao-wen²，WANGLi-li²，LI Xiao-yu²，CONGCongl （1.CollgofssdLifeieKbatHdlginLigProlOaUnvesitylaniog， China;2.SofgAloteoldutriLboatorliUsiyho China）

Abstract：Theuseofantibioticsisprimarymethodofcombatingbacterialpathogens，whichhasledtoisuessuchasantibioticresidues，enviromentalplution，andtheincreaseimultidrgesistantbacteriatherebycalatingtheifcultyininfectiootro Asnaturalpredatorsofbacteria，acteriophagesoferedapromisingalternativewithsubstantialpotential.Bacteriopageendolysinwas acellwall peptidglyanhydrolasertansglycoidase，nddepolmerassdgadedextracelularatrixplyaccharides，hichehibitedhigheficacyandspecificityinlysingbacterialcels.Thisreviewsummarizedrecentadvances inendolysinanddepolyerase fromVibriobacteriopagesandteirapplicatiosinpathogencontrol.Teimastoprovideinsightsandrferencesforresearsdeveloping novel，eco-friendly antibacterial agents.

Key Words： bacteriophage;endolysin;depolymerase;Vibrio sp.

弧菌属（Vibriosp.）是一类普遍存在于水域环境中的革兰氏阴性菌[1]。（剩余12367字）