如皋地区老年人HIV感染筛查中假阳性的影响因素分析

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Analysis of Influencing Factors of False Positives in HIV Infection Screening among the Elderly in RugaoRegion/JIN Xin，GAO Lingyun.//Medical Innovationof China，2025，22（29）：148-151

[Abstract]Objective： To analyze the influencing factors of false positives in HIV infection screening among the elderly in Rugao region.Method：Thisstudy wasaretrospective study.TheHIV infectionscreeningdata of the elderly in Rugao region from May 2O21 to August 2O24 were collected and statisticall analyzed.logistic regression was used toanalyze the influencing factorsof false positive HIV infection.Result：From May 2O21 to August 2024， a total of 442665 cases of HIV infectionamong the elderly were screened， with 48 confirmed cases and 48 false positive cases.Theresults of univariateanalysis showed that there were statistically significant diferences in the HIVinfection test results among subjects of diferent gender，age，ducationallevel，marital status，occupation， disease，household registration，and polypharmacy （ P <0.05）. The results of logistic regression analysis showed that gender，age，educational level，marital status，occupation，disease，householdregistration，and polypharmacywere risk factors for false positive HIV infection （ P <0.05）.Conclusion：In the HIV infection screening of the elderly in Rugao region，gender，age，educational level，marital status，occupation，disease，household registrationand polypharmacy are risk factors for false positives.

[Keywords] Rugao regionElderly population Human immunodeficiency virus screening g False positivesInfluencing factors First-author'saddres：DepartmentofMicrobialLaboratory，Rugao Center forDiseaseControland Prevention，Rugao22650o，China doi：10.3969/j.issn.1674-4985.2025.29.035

艾滋病是获得性免疫缺陷综合征（acquiredimmunodeficiencysyndrome，AIDS）的简称，是由人类免疫缺陷病毒（human immunodeficiency virus，HIV）感染引起的一种严重传染病，可导致 CD4+T 淋巴细胞减少，并引发机会性感染、恶性肿瘤及中枢神经系统病变，是全球重大公共卫生挑战之—[-3]早期检测是发现HIV感染的关键手段，扩大检测范围对艾滋病的防治至关重要[4-6]。（剩余4277字）