经尿道铋激光膀胱肿瘤整块切除术治疗非肌层浸润性膀胱癌的临床效果

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Clinical Effect of Transurethral Holmium Laser Bladder Resection Tumor in the Treatment of Nonmuscle Invasive Bladder Cancer/ZHANG Hongge.//Medical Innovationof China，2025，22（24）： 046-049

[Abstract]Objective：To explore the clinical efect of transurethral holmium laser bladder resection tumor for non-muscle invasive bladder cancer （NMIBC）.Method：A total of 8O patients with NMIBC who admitted in from December 2O21 to September 2O23 were selected，and they were randomly divided into the study group （n=4O） and the control group（ n =40）.The control group was received transurethral resection of bladder tumor （TURBT） treatment， while the study group was received transurethral holmium laser bladder resection tumor treatment.The perioperative indicators， tumor markers，recurrence rate and complications in two groups were compared. Result： The amount of bleeding in the study group was lessthan that in the control group，and the bladder irigation，indweling catheter and hospitalization time were shorter （ P <0.05）; at 6 months after surgery，the levels of urinary fibrinogen degradation products （FDP），carcinoembryonicantigen （CEA）andcytokeratin19 fragment（Cyfra21-1） intwogroupsdecreased，andthoseinthestudygroup were lower than those in the control group（ P <0.05）; the recurrence rate of the study group was 5.00% （2/40），which was lower than 22.50% （9/40）of the control group （ P <0.05）; the incidence of complications in the study group was 7.50% （20 （3/40），which was lower than 27.50% （11/40） in the control group （ P- <0.05）. Conclusion： Transurethral holmium laserbladder resection tumor inthe treatmentof patients with NMIBC can shorten the indwellingcatheter，bladder irigation，hospitalization time，reduce intraoperative blood loss，reduce tumormarkerlevels，and reducerecurrence and complications.

[KeyWords] Non-muscle invasive bladder cancerTransurethral holmium laser bladder resection tumor Transurethral resection of bladder tumor

First-author'saddress：Department of General Surgery，， 277599， China doi：10.3969/j.issn.1674-4985.2025.24.011

膀胱癌是泌尿系统恶性肿瘤的一种，具有较高的发病率，其中最常见的类型为非肌层浸润性膀胱癌（NMIBC）[1]。（剩余5412字）