熵权法联合星点设计-响应面法优选薄荷超微粉碎工艺优化

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关键词：薄荷（MenthahaplocalyxBriq.）；熵权法；星点设计-响应面法;超微粉碎;工艺优化

中图分类号：R248.1 文献标识码：A

文章编号：0439-8114（2025）06-0161-06

DOI：10.14088/j.cnki.issn0439-8114.2025.06.027 开放科学（资源服务）标识码（OSID）：

Optimization of the ultra-fine crushing process for Mentha haplocalyx Briq. by entropy weight method combined with central composite design-response surface methodology

CHEN Xue-ting1，ZHANGJian-jun1，HE Cheng-yan²

（1.GuangdongScondTraditioal Chinese Medicine Hospital（GuangdongResearch InstituteofTraditional Chinese MedicineManufac turing Technology）/Guangdong ProvincialKeyLaboratoryofResearchandDevelopmentinTraditionalChinese Medicine，Guangzhou 510095，China；2.Hubei University of Medicine，Shiyan ，Hubei， China）

Abstract：Usingcentralcompositedesign-responsesurface methodology，thecomprehensivescorevalues of volatilecomponentssuch as mentholandmenthone，nonvoltileomponentssuchsochlorogenicacid，rotocateualdehde，utin，aringin，spridin， rosmarinic acid，quercetin，and the average particle size of D90 ，were used as indicators to optimize the three influencing factors of watercontent，dosage，andgrindingtimeforultra-finecrushingofMenthahaplocalyxBriq.Resultsshowedthattheoptimalultrafine grinding process for M. haplocalyx Briq. was to control the water content of the slices at 6.0% ，with a grinding time of 18 min and a dosageof 70g .Theultra-fine grinding process of M .haplocalyx Briq.optimized by central composite design-response surface methodology was simple and fast，and the obtained model had a high degree of fit and good predictability.

Key words：Mentha haplocalyxBriq；entropyweight method;centralcompositedsign-responsesurface methodology；ultra-fine crushing; process optimization

薄荷为唇形科植物薄荷（MenthahaplocalyxBriq.）的干燥地上部分，具有疏散风热、清利头目、利咽透疹、疏肝行气的功效。（剩余7310字）