肠道菌群失衡在原发免疫性血小板减少症中的研究进展

[Abstract]Primary immune thrombocytopenia （ITP） is a hemorrhagic autoimmune disease characterized by increased destructionand decreased productionof platelets.As the most widely distributed balance hub in the human body，the mechanism of intestinal microecological immunity in diseases has gradually become a research hotspot.Studying the imbalance of gut microbiota，the trends ofchanges inmicrobiotaand metabolic products，and their associations with diseases may reveal new strategies for preventing and treating diseases by regulating the balanceof gut microbiota.Thisarticle reviews theresearch progressof gut microbiota inITP，explores the potential connections between gut microbiota and itas wellas the latest therapeutic directions，and discusses the possibilityof gut microbiota as a biomarker and therapeutic target.

[Keywords] Gut microbiota Primary immune thrombocytopenia Immune disease

First-author'saddress：Hematology Centerof theFirstAffiliated Hospital of XinjiangMedical University， Urumqi 830054，China doi：10.3969/j.issn.1674-4985.2026.07.038

原发免疫性血小板减少症（primaryimmunethrombocytopenia，ITP）是一种复杂的自身免疫性疾病，是临床上较多见的因为体液免疫和细胞免疫异常等血管外因素所导致的出血性疾病。（剩余8176字）