不同时机电子支气管镜灌洗术治疗儿童大叶性肺炎合并支气管黏液栓的效果对比

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[Abstract]Objective：To explore the application value of electronic bronchoscopy lavage at diferent times inthe treatment of children with lobar pneumonia （LP）complicated with bronchial mucus plugs.Method： A total of 95 children with LP complicated with bronchial mucus plugs admited to North Anhui Coal and Power Group General Hospital from October 2O19 to October 2O22 were selectedand divided into the early group （with a disease course of 5-10 days，48 cases）and the late group （with a disease course of 11-21 days，47 cases） according to the disease course stage atthe time of admission and diagnosis.Both groups were treated with electronic bronchoscopy lavage on thebasis of conventional treatment.The therapeutic effects，symptom improvement time，levelsof cytokines [CRP，D-D，procalcitonin （PCT），lactatedehydrogenase （LDH）beforeandafter lavage，and incidenceof complications between the two groups were compared.Result： The total efective rate of the early group was higher than that of the late group （ P <0.05）. The time for fever to subside， cough to disappear and lung rales to disappear in the early group were all earlier than those in the late group（ P<0.05 ）. At3 and7 daysafter lavage，CRP，PCT，LDH and D-D in the early group were lower than those in the late group （ P <0.05），and there were intergroup effects，time effects and interaction effects of CRP，PCT，LDH and D-D（ P <0.05）.There wasno statistically significant difference in the incidence of complications between the two groups （ P >0.05）. Conclusion：Early treatment with electronic bronchoscopy lavage for children with LPcombined with bronchial mucus plugs has significant efects，reducing inflammation and aleviating symptoms，and is highly safety.

[Keywords]Lobar pneumoniaBronchial mucus plugsElectronic bronchoscopyInflammatory response Safety

First-author'saddress：Pediatrics Department，North Anhui Coaland Power Group General Hospital， Suzhou234000，China

doi：10.3969/j.issn.1674-4985.2026.07.017

大叶性肺炎（LP）是社区获得性肺炎患儿住院的重要原因之一，其病情隐匿，症状不典型，易延误治疗时机[-2]。（剩余5618字）