耳后与鼓室注射地塞米松治疗伴2型糖尿病的特发性突聋患者的效果对比

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[Abstract] Objective： To compare the clinical effects of retroauricular and tympanum injection of Dexamethason in the treatment of patients with idiopathic sudden sensorineural hearing losscomplicated with type 2 diabetes mellitus （T2DM） and its influence on blood glucose levels.Method：This study included 68 patients with idiopathic sudden sensorineural hearing losscomplicated with T2DM who were hospitalized in Department of Otolaryngology，Nantong Haimen Hospital of TCM from June 2O22 to December 2O24.The patients were divided into the retroauricular group （ n =34） and the tympanum group n =34） using the random number table method.Both group were given the conventional basic treatment，Dexamethason was injected into theretroauricular and the tympanum， respectively，at a dose of 5 mg each time，once every other day，for atotal of5 times.The total treatmentcourse was1O days.The clinical eficacy，incidence of adverseeventsand blood glucose levelsof the two groups were compared.Result：There were no statisticallysignificant differences inthecurerate，improvementrate，effective rate，ineffectiverateand total efectiveratebetween theretroauricular groupandthe tympanum groupafter treatment 0 P>0.05 . The incidence of vertigo in the retroauricular group was lower than that in the tympanum group （ P <0.05）. There were no statistically significant differences in the incidence of tympanic membrane perforation， middle ear infection and local bleeding between the two groups （P>0.05） .There were no statistically significant diferences in

fasting blood glucose and 2h postprandial blood glucose levels after treatment between the two groups （P>0.05） Conclusion：For patientswith idiopathicsuddensensorineural hearing losscomplicated with T2DM，theclinical efficacy of retroauricular and tympanum injectionof Dexamethason is comparable，and it has no significant effecton blood glucose levels.However，retroauricular injection can reduce the risk of vertigo.

[Keywords] Retroauricular injection Tympanum injectionDexamethason Type 2 diabetes mellitus Idiopathic sudden sensorineural hearing loss

First-author's address： Department of Otolaryngology，Nantong Haimen Hospital of TCM，Nantong 226100， China

doi：10.3969/j.issn.1674-4985.2026.07.029

特发性突聋是原因不明的突发性感音神经性听力下降，多伴耳鸣、眩晕等症状，其发病机制可能与病毒感染、微循环障碍及免疫因素有关[1。（剩余5398字）