长期血液透析导管相关性感染病原菌类型及影响因素

打开文本图片集

[Abstract]Objective：To analyze the types of pathogenic bacteriaand influencing factors ofcatheterrelated infections （CRIs）in long-term hemodialysis.Method： The clinical data of 66 long-term hemodialysis patients in from August 2O21 to March 2O23 were retrospectively collected.The patients were divided into the occurrence group （ n =22）and the non-occurrence group （ n =44） according to whether CRIs occurred.The types of pathogenic bacteria infected in CRIs patients were statistically analyzed， and the influencing factors of CRIs occurrence inlong-term hemodialysis patients were analyzed.Result： Among 66long-term hemodialysis patients，a total of 22 cases of CRIs occurred， with an infection rate of 33.33% . Through bacterial culture identification， Gram-positive bacteria accounted for the highest proportion （59.09 % ，13/22）， followed by Gram-negative bacteria （31.82 % ，7/22），and fungal infections （9.09 % ，2/22）. There were significant differences inage，dialysis time，catheterization time，nutritional status，useofantibiotics，andtransferinunsaturation between the two groups （ P <0.05）.logistic regression analysis showed that dialysis time ⩾3 years，catheterization time ≥2 weeks，no useof antibiotics，and transferin unsaturation were independent risk factors for CRIs inpatients with long-term hemodialysis（ P <0.05）.Conclusion：Gram-positive bacteria are the most common pathogenic bacteria in CRIs patients undergoing long-term hemodialysis.Long dialysis duration，long catheterization duration， non-use of antibacterialdrugs，and unsaturated transferrinare independentrisk factorsforCRIsinlong-term hemodialysis patients. Clinicaly，more attention should be paidto this group ofpeople，and corresponding measures should be taken in a timely manner to intervene and reduce the occurrence of CRIs.

[Keywords] HemodialysisCatheter-related infectionsPathogenic bacteria Influencing factors Dialysis time

近年来我国的肾脏疾病患病人数明显上升，血液透析是终末期肾病（ESRD）最主要的治疗方式，能够有效清除体内代谢废物和多余水分，维持内环境稳定，从而延长患者生命，改善患者的生存质量[-2]。（剩余5321字）