输尿管软镜碎石术联合可弯曲负压吸引鞘治疗肾结石的临床效果

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[Abstract]Objective： To investigate the clinical efficacy of the combination therapy offlexible ureteroscopic lithotripsyand flexible negative pressure suction sheath forrenal calculi.Method：From January 2O23 to December 2024，100 cases of renal calculi who treated in Gao'an People's Hospital were selected and divided into two groups with random number table method，with 5O cases in each group.The control group were provided with flexible ureteroscopic lithotripsy，andon this basis，the observation group aditionally took flexible negative pressure suction sheath on the basis of thecontrol group.Thecomparisons were performed onperioperative indicators，renal function， levels of inflammatory factors inboth groups.The two groups were evaluated and compared in terms of postoperative pain degree.The stoneclearance rateand incidence ofcomplications were statisticallyanalyzedand compared in both groups.Result： The observation group had lessintraoperative blood loss，shorter operation timeand postoperative double-J stent placement time than those of the control group （ P <0.05）. The observation group obtained higher stone clearance rate and lower incidence of complications compared with those of the control group （ P <0.05）. The observation group demonstrated lower postoperative 6，24 and 48 h VAS scores than those of the control group （ P <0.05）. There were no statistically significant diffrences in Scrand BUNbetween the two groups before the operation and one week after the operation （ P- 0.05）.The observation group achieved lower postoperative 24 h procalcitonin （PCT），WBC and CRP than those of the control group （ P- <0.05）.Conclusion：The treatment of flexible ureteroscopic lithotripsy combined with flexible negative pressure suction sheath for patients with renalcalculi canreduce intraoperative blood loss，shorten the operationtimeand postoperativecatheterization time，alleviate postoperative painand inflammatory responses，improvethe stone clearancerate，reduce the incidenceof complications，and does notaffect renalfunction.

[Keywords]Renal calculiFlexible ureteroscopic lithotripsyFlexible negative pressure suction sheath Perioperative indicatorsPain degreeRenal function Inflammatory factors

First-author'saddress： Department of Urology，Gao'anPeople's Hospital， Gao'an 33o8oo，China doi：10.3969/j.issn.1674-4985.2026.07.007

肾结石作为泌尿系统常见疾病，且近年来呈上升趋势，全球发病率为 1%～15% ，会引发肾绞痛、血尿等症状，严重还会损害肾功能[1-2]。（剩余5297字）