肺心下腔静脉综合超声联合BNP对心源性呼吸困难的鉴别诊断价值

打开文本图片集

[关键词］肺心下腔静脉综合超声；利钠肽，脑;呼吸困难；心力衰竭；诊断，鉴别[中图分类号]R441.8 [文献标志码］A [文章编号] 2096-5532（2025）03-0387-04doi：10.11712/jms.2096-5532.2025.61.071 [开放科学（资源服务）标识码（OSID）

[网络出版]https：//link.cnki.net/urlid/37.1517.R.20250627.1107.003； 2025-06-27 16：32：21

Valueoflung-cardiac-inferiorvenacavaintegratedultrasoundcombinedwithbrainnatriureticpeptideinthdiferentialdiagnoisof cardiogenic dyspneaGAO Shuaishuai，GENG Yun，LIU Yong（Departmentof Ultrasound，Qingdao Hiser Hospital ffiliated to QingdaoUniversity，Qingdao 266o33，China）

[Abstract]ObjectiveToinvestigatethevalueof lung-cardiac-inferior venacava integratedultrasound combined withbrain natriureticpeptide（BNP）inthedifferentialdiagnosisofcardiogenicdyspnea.MethodsAtotalof115patientswithacutedyspnea who wereadmitedtoQingdaoHiserHospitalAffliatedtoQingdaoUniversityfromOctober2O2 toSeptember2023wereenrolledassubjects，andacording tothefinaldiagnosis，theyweredividedintocardiogenic groupwith6Opatientsandpulmonary group with 55 patients.Lung-cardiac-inferiorvena cava integratedultrasound was performed and serum BNPlevel was measured within 2h afteradmission.Thecorrelationof the total numberof B-lines with BNP，leftventricular ejection fraction（LVEF），and inferiorvenacavacollapseindex （IVC-CI）wasanalyzed，andthereceiveroperating characteristic（ROC）curvewasused toaalyze thevalueoflung-cardiac-inferiorvenacavaintegratedultrasoundcombinedwithBNPinthediagnosisofcardiogenicdyspnea.ResultsThe total number of B-lines was linearly positively correlated with BNP（ '=0.681，P<0.05⟩ and was linearly negatively correlated with LVEF and IVC-CI in both groups （r=-0.408，-0.465，P<0.05） . The ROC curve analysis showed that the total numberof B-lines，LVEF，IVC-CI，and BNPused alone or incombination had an area under the ROCcurve（AUC）of 0.822， 0.763，0.822，0.881，andO.979，respectively，suggesting that each indicatorused alonehadalower AUCthanthecombinationof the four indicators （ ⋅P<0.05⟩ .Conclusion Lung-cardiac-inferior vena cava integrated ultrasound combined with BNP has a high valuenthediagnosisofcardiogenicdyspneaandcanprovideanimportantbasisfortherapiddiferentialdiagnosisofcardiogenic dyspnea in clinical practice，and therefore，it holds promise for clinical application.

[Key words]lung-cardiac-inferiorvenacava integratedultrasound;natriuretic peptide，brain；dyspnea；heartfailure;diagno sis，differential

呼吸困难是急诊最常见的症状之一[1]，病人主观上感到呼吸费力，其病因多种多样，主要分为心源性呼吸困难和肺源性呼吸困难[2]，心源性呼吸困难的主要原因是急性心力衰竭（AHF）[3]。（剩余8960字）