运用六经辨证结合经方治疗对膝骨关节炎（肝肾亏虚证）患者VAS评分及炎症因子的影响

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中图分类号：R684.3 文献标识码：A文章编号：1006-1959（2025）23-0058-05

DOI：10.3969/j.issn.1006-1959.2025.23.010

Effectof Syndrome Differentiation of Six Channels Theory Combined with Classical Prescriptions onVAS Score and Inflammatory Factors in Patientswith Knee Osteoarthritis （Liver-kidneyDeficiency Pattern）

ZHU Shenghu，ZHENG Juntang，LI Yaling （TheSecond Departmentof Orthopedics and Traumatology，Wuwei Hospital of Traditional Chinese Medicine，

Wuwei ，Gansu，China）

Abstract：Oetitaetifoftofielsoalpi sodiuhauoateecttsieaiiedalito （VAS）osteoartride（CndatoctoelsetsAotalftisdiedtowesitalofdoal ChineseMedicinefromOctober2O2OtoOctober21weredividedintotworoups（ontrolgroupandoservationgroup）byrandomumbertable methodithtitsihouoatditartilaeofduoateodti groupwastradidietifalsdasalpreitososieotalitt WOMAC（pain，stiffness，physiological function） score，VASscoreand MMP-3，IL-1and TNF- ∇⋅αα∝ levels in synovial fluid beforeand after treatment were compared between the two groups.Results The total effective rate of the observation group（ 92.68% ） was higher than that of the control group （73.17 % ）（P<0.05）.After treatment，theWOMAC score of theobservation group was lower than thatof the control group（ P<0.05 ，theVASscore was lower than that of the control group（ P<0.05 ），andthelevelsofMMP-3，IL-1andTNF- αααααααααααααααααααααααααααααααα in thesynovial fluid were lower than those in the control group（O.）ceatoofiaelsdalptielrothee ofeosteaiialoitotdo response，which has important clinical application value.

Keyord：al index score; Inflammatory factors

膝骨关节炎（kneeosteoarthritis，KOA）是临床常见的退行性关节疾病，以关节软骨损伤、滑膜炎症、骨质增生为主要病理特征，临床表现为膝关节疼痛、僵硬、活动受限，严重时可导致关节畸形，影响患者生活质量I。（剩余7728字）