双水平无创呼吸机对肺源性心脏病合并睡眠呼吸暂停慢性心力衰竭患者的影响
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AbstractObjective：Toevaluatethemedicalvalueofbi-levelnon-invasiveventilationinthetreatmentofwithchronicheart failurecomplicatedwith pulmonary heartdiseaseandsleepapnea.Methods：Atotalof6O patients with chronic heartfailure with thecomplicationofpulmonaryheartdiseaseandsleepapnea whoadmited inthehospitalfromJanuary2O22toDecember2023 were enroledand evenly divided intoacontrol groupandanobservation group byrandom numbertable.Thecontrolgroup receivedroutinetreatment，hiletheobservationgroupaditioalhadbi-levelnon-invasiveventilationtreatmentTheresultsofindicators were observedandcompared between thetwogroups.Results：Afterthetreatment，thearousal indexof theobservation group waslowerthanthatofthecontrolgroup，thelowestbloodoxygensaturationatnightwashigherthan thatofthecontrol group，and the apnea index was lower than that of the control group，with statistically significant diferences（ P<0.05） . In terms of polysomnography（PSG）indicators，therespiratory disturbance indexandoxygen desaturationindexof theobservation group waslowerthanthoseofthecontrolgroup，theaverageblodoxygensaturationwashigherthanthatof thecontrolgroupanddifferences between the two groups were statistically significant（ P<0.05 ）. For overall sleep quality，the wakefullness after sleep onset of patientsintheobservationgroupwasbeterthanthatinthecontrolgroup，thelongestsleepdurationwasbeterthanthatinthe control group，and thePSQIscore was lower than that in thecontrol group，with statistically significant differences（ P<0.05） . Afterthe treatment，theincidenceofpoor sleepintheobservatio groupwaslowerthanthatinthecontrolgroup，showingthatthere was a significant difference（ P<0.05） . Conclusion： In the treatment of patients with heart failure combined with pulmonary heart disease andslepapnea，theapplicationof bi-levelnon-invasive ventilationcaneasesymptoms，promoteregularizationof thepatients‘nocturmal breathingrhythm，getback thenormal sleepstages，andsignificantlyimproveslepqualityandcontroladverse sleep conditions such as sleepiness.
KeywordsPulmonary heart disease;Sleepapnea；Chronic heart failure；Bi-level non-invasiveventilator;Sleepquality；Respiratory rhythm；Sleepiness；Oxygen desaturation index
中图分类号：R541.5;R338.63 文献标识码：A doi：10.3969/j.issn.2095-7130.2025.04.015
睡眠是一种自然的生理现象，其本质是一种脊椎动物自我主动调节的过程，目的是维持生命活动而进行的适当休息。（剩余5177字）