心率变异性指标对阻塞性睡眠呼吸暂停低通气综合征患者病情的评估价值

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AbstractObjective：Toobservetheaplicationof heartratevariability（HRV）indices inassssng diseaseseverityinpatients withobstructivesleepapneahypopnea syndrome（OSAHS）.Methods：Atotalof168OSAHSpatientsadmited to Xingyi People's Hospital from January2O24to January 2O25 were selectedas theresearch subjects.Basedonthe apnea-hypopnea index（AHI）， patients were divided into a mild group（AHI 5 to 15 events/h） and a moderate-severe group（ AHI>15 events/h） . Baseline characteristics and HRV indices were compared between the two groups.Thecorelation between HRV indices and sleep parameters， as wellas thevalueofHRVinasssing OSAHSseveritywere analyzedResults：The moderate-severe groupshowedsignificantly lowervalues inallHRVindicescomparedtothe mildgroup，including thestandarddeviationof allnormalRR intervals（SDNN）， root mean square of succesiveRR interval differences（rMSSD），percentage of adjacent RR intervals difering by >50 ms （pNN50），and high-frequency power（HF）（ P<0.05 ）. Pearson correlation analysis revealed that sleep latency，percentage of deep sleep，and percentageofREMsleep were positivelycorelated withHRVparameters，whiletotal sleep time，sleepeffciency， percentage of light sleep，and number of nocturnal awakenings were negatively correlated with HRV parameters（ P<0.05 ）. ROC curve analysis demonstrated that HRV indices havecertain value in assessing OSAHS severity.Conclusion：HRV indicatorsare correlated withOSAHSslee indicatorsandcanserve asimportantauxiliarytools forassessing theseverityofOSAHSand predicting cardiovascular risk.

KeywordsObstructive sleep apnea hypopnea syndrome；Heartrate variability；Medical condition；Prediction；High frequency power； Sleep quality；Apnea-hypopnea index； Correlation analysis

中图分类号：R364.4;R338.63 文献标识码：A doi：10.3969/j. issn.2095-7130.2025.04.012

阻塞性睡眠呼吸暂停低通气综合征（ObstructiveSleep Apnea Hypopnea Syndrome，OSAHS）不仅影响患者的生命质量，还与心血管疾病、代谢综合征等多种并发症密切相关[1]。（剩余5237字）