沙库巴曲缬沙坦钠治疗慢性心力衰竭的临床效果及对血清NT-proBNP的影响

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中图分类号:R541.6 文献标识码:A文章编号:1006-1959(2025)17-0142-04
DOI:10.3969/j.issn.1006-1959.2025.17.025
Clinical Effect of Sacubitril Valsartan Sodium in the Treatmentof Chronic Heart Failure and its Effect on Serum NT-proBNP
WEIBin
(DepartmentofCardiology,GuangchangPeople'sHospital,Guangchang3449Oo,Jiangxi,China)
Abstract:ObjetieTxplolicaletofubirlasarasoinreamtofocartfureditso terminalprobrect(petsUingdbablethtotalytitsicre admitedtoGuangangCoutyeoplesHospitalfroJauarytoDecember2weredividedintocontrolgoupndsudygouptits pergroup.Inteotroloupatientseretreatedithenazepildrochlodblets,ileintesudyouatitseretedit sacubitrilbaldsEEd andincidencefseactiooalliverfuioadchseekaleipealearepedet groups.Results The study group (96.97 % ))hadhigherthe total efectiverateof treatment thanthat inthecontrol group (72.73 % ) (P<0.05).The study groupdemonstratedsignificantlyetercardiacfunctionparametersandNproBlevelcomparedtothecontrolgroupaftertreatent( P< 0.05).The study group (3.03 % ) had lower the incidence of adverse reactions than that in the control group (18.18 % 0 P< 0.05).Conclusion The clinical effct of sacubitrillaataofocartflueschpdacciftspelf serum NT-proBNP,and has high safety.
KeyWords:Sacubitril valsartan sodium; Chronic heart failure;Cardiac function;NT-proBNP
慢性心力衰竭(chronicheartfailure)是临床上发生率较高的一类心脑血管疾病,主要由心脏长期血液输出量减少引起心室重塑所导致,对患者的心功能产生严重影响,具有发病率高、死亡率高的特点,4年生存率约等于恶性肿瘤,且若患者病情严重,1年内的死亡率可以达到 50% 左右,可见给予慢性心力衰竭患者有效治疗十分重要[2]。(剩余5207字)