单硝酸异山梨酯注射液对射血分数保留心力衰竭患者运动耐力及生活质量的影响

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中图分类号：R541.6 文献标识码：A

DOI：10.3969/j.issn.1006-1959.2025.17.018 文章编号：1006-1959（2025）17-0112-05

Effect of IsosorbideMononitrateInjectionon Exercise Toleranceand QualityofLife inPatientswithHeartFailurewithPreservedEjectionFraction

ZHANG Wenyong

（Departmentof Cardiovascular Medicine，Ji'an CountyPeople'sHospital，Jian3431Oo，Jiangxi，China）

Abstract：OjeiTivesttofosoooateietiooeeeleacedalitoflifeipattsiat failurewithpreseedetiofractioMetdsotalfatitsiartflureitresedectiofractoditdtot People'sHospialfrouaytgstedsehtcodingtodoubrbleode dividedntocontrolgoupdstudyoupith3Opatientsachoup.Theontrolgoupastreatedwithroutietreatmentndthesudyoup wastreatediutitdeeialccie dizinessd）dutdeec levelsgl endurancealfilalcolcalctalalalityedo total effective rate of treatment in the study group （96.67 % ）was higher than that in the control group（73.33 % ）（P<0.05）.The incidence of adverse reactions in the study group （3.33 % ） was lower than that in the control group （23.33 % ） P< 0.05）.After treatment，the CO，SV，CIand EFof the two groupswerebetertantosebeforetreatendthCO，S，ndEFfestudygrouperebetrtanthoseofeotrolop Pe <0.05）. Aftertreatment，televelsofTG，TCandLDL-Cintestudygroupwerelowerthanthoseinthecontrolgroup，hilethelevelsofHDL-Cwere higher than those in the control group（ P<0.05 ）.The 6 MWTof the two groups after treatment was higher than that before treatment，and the6 MWT ofthestudyoasraatfooOfereattosofiolalctioiio mentalhealthdialfouranoforreatdsflocalucoiolalctio mental health and vitality of the study group were higher than those of the control group （ P< 0.05）.Conclusion Isosorbide mononitrate injection has a definiteclinicalintreaeofisiartfuewireseedetiofractioItanprotadacfunctiodblo lipidleveloftitspoveduraedalififftdsetyorhl

Keywords：Isosorbide mononitrateinjection;Heartfailurewithpreservedejectionfraction;Sports endurance; Qualityof life

射血分数保留心力衰竭（HFpEF）是临床针对LVEF⩾50% 的心力衰竭特殊类型，表现为充血症状，如水肿、呼吸困难等，是心脏结构和功能异常导致的临床综合征。（剩余6007字）