高密度PDMS微孔薄膜的制备方法

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Abstract:Aimingattheelasticarraymicroporousfilmsneededfororganchipresearch,methodsformaking polydimethylsiloxane(PDMS)-basedfilmswithhighdensityarrymicroapertureswerestudied,includingtheinfluenceofsuface propertiesofsilicon-basedtemplates,pouringandcuringofthePDMSfilms.Condionsandpelingoftheflms fromthe silicon-basedtemplates.Accordingtovisualobservationandlaserscannerdetectionresults,thesilicon-basedtemplatecoated withSiO2onthesurfacewastreatedwithfluorosilane.Basedonacuratelycontroling thepouringamountandcuring temperature,itwasfurthersubjectedtogravity-asistedpressure-retainingcuring,andcoveredwith PDMSThePCfilmcured togetheron the PDMS completely peeled offthearray microporous PDMS film from the silicon template.

Keywords:polydimethylsiloxane;porous membrane;silicon wafer; silanization; experimental equipment

聚二甲基硅氧烷(Polydimethylsiloxane,PDMS)多孔薄膜,是近年来备受关注的器官芯片的关键组件,用作细胞共培养的支撑载体或物质交换的通道等[I-3]。(剩余3726字)

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