IgG4相关性疾病的诊疗研究现状

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[Abstract]IgG4-related disease（IgG4-RD）isasystemicautoimmune disordercondition largelydistinguished bypersistent inflammationandfibroticalterations.TheetiologyandpathogenesisofIgG4-RDarenotfullelucidatedbutmayinvolveinflamatory mediators，cllaruityndosisofuticotaagosisceiatesooguatioofroloicale tions，imagigrsltsndclinicalanifestatios.isdiseasecanimpactsevralogansandisues，withlinicalpresetatiolas sifiedintosystemicsptoms，rganspecificsptoms，andma-likelsions.Treatmentmodaiesencompassgucocoticoids，immunosuppressnts，ntibod-argeedtreaments，dificationofgutmcobtandprosptieoinatimediesscleis to examinrecentdevelopmentsinthepathophsiology，clinicalsymptoms，diagnosis，andtreatmentapproachsofIgG4-RDering fresh perspectives for future clinical management.

[Key words] IgG4-related diseases；Pathogenesis；Advances in diagnosis and treatment；Current state of research

IgG4相关性疾病（IgG4-relateddisease，IgG4-RD）是一类免疫介导的慢性炎症性疾病，主要表现为血清IgG4水平的显著升高。（剩余15771字）