原发性胆汁性胆管炎预后模型的演进与应用

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Abstract：Primarybiaycholangitis（PBC）isanautoimmuneliverdiseaseoftenobservedinmidle-agedwomen.Theearlyclinical symptomsofPBCarenotbvious，anditcanprogresstolivercihosisandleadtovariouscomplicatios.Usodeoxyholicacid（UDCA）is themostefectivedrugforthetreatmentofPBC，butabout40%ofthepatientsarestillinsensitivetoUDCA，whichcanleadtoslow progressionofthedisease.AccurateasessmentofdiseaseconditionsandpatientprognosiscanhelpooptimizetreatmentgiensThis aiticle reviewstheresearchadvances in prognostic models forPBC，inordertoprovideareferenceforclinicaltreatment.

Keywords：PrimaryBiliary Cholangitis；Prognosis；Model

近年来原发性胆汁性胆管炎（primarybiliarycholangitis，PBC）发病率及患病率均呈增高趋势[1-3]，发病机制尚不清楚[45]。（剩余14834字）