原发性胆汁性胆管炎与肠道菌群

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Abstract:Inrecentyears,anincreasingamountofevidencehasshownthatintestinalflora disturbanceplaysacriticalroleinthe pathogenesisofprarliayolangis(BC).IntestialfoaparticipatesiteevelopetdprogessiofBCyoulatigile acidmetaboism,afectingimunesystemfunctions,ndmediatinginteractionswithintegut-liveraxis.Thisarticlesummrizesthe pathophysiologicalfeaturesofPBC,elaboratesonthemechanismofactionof testinalflorainPBC,andanalzesthepotentialtreatent strategiesbasedonntestialforareglationdtoprovidetoreticalassfortealyagosisdprseramntofP.
Key Words:PrimaryBiliary Cholangitis;Gastrointestinal Microbiome;BileAcidsandSalts;ImmuneSystem
原发性胆汁性胆管炎(primarybiliarycholangitis,PBC)是一种主要累及中年女性的自身免疫性肝病[1]。(剩余13166字)