BIS指导下丙泊酚闭环靶控输注麻醉方式用于机器人辅助胰十二指肠切除术的效果研究

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中图分类号R614 文献标识码A文章编号 2096-7721（2025）12-2060-06

AbstractObjective：Toanalyetheclncaleficacyofbispetralindex（BS）gudedlosed-optargetcontroledifusionofpopofol inrobot-assted pancreaticoduodenectomy （RAPD）.Methods：Aretrospectiveanalysis asconductedon102 patientshouderwent RAPDintheFirstAfiliatedHospitalofXi'anJiaotong UniversitybetweenOctober2O23andNovember2O24.Patientsweredivided intothecontrolgroup（n5，eceivigopen-looppropofolinfusion）andtestudygoup（=51，eceivingguidedcosed-lare controledinfusinofpropofol）basedonanesthsiatechnique.Perioperativeindicators，emodynamicparameters，cognitivfution， andadversereactionrates werecomparedbetwenthetwo groups.Results：Thestudy groupshowedsignificantlyshorterdurationsof anesthesiamaintenance，mergence，extubationduringrecovery，andspontaneous breathingrecoverycompared tothecontrolgroup 0 P 05）.AtT（1.5oursafterproofolinfusioninthecontrolgroup/ourafterclosed-loosystem activationinthestudy group），thestudygroupshowedlowerHRandhigherMAPthantecontrolgroup.Attheimmediateendofurgery （T3），the study group showed lower HR and higher MAP than the control group （P<0.05） .No significant difference was observed in minimental state examination （MMSE） scores between the two groups one day after surgery （P>0.05） ， but the study group showed significantly higher MMSE scores at 1 day and 3 days after surgery compared to the control group （P<0.05 ）.The incidence of adverse reactions was also lower in the study group than the control group （P<0.05） . Conclusion： BIS-guided closed-loop target-controlled infusion of propofol can accelerateposopeatieoerydeofolosutiotabilemdaisroetopatiegitieid lowerthe incidence of adverse reactions inpatientsundergoingRAPD.

KeyWordsBispectral Index;Propofol; Closed-looTargetedInfusion;Robot-assistedSurgery;Pancreaticoduodenectomy

胰十二指肠切除术是肝胆外科最复杂的手术之一，操作难度大、手术时间长、对麻醉管理要求极高[。（剩余11608字）