叶酸联合阿托伐他汀对脑梗死合并高同型半胱氨酸患者 近期疗效及神经功能的影响

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中图分类号：R743.33 文献标识码：A DOI：10.3969/j.issn.1006-1959.2025.16.026

文章编号：1006-1959（2025）16-0126-05

Folic Acid Combined with Atorvastatin on Short-term Eficacy and Neurological Function in Patients with Cerebral Infarction Complicated with Hyperhomocysteinemia

LIAO Chunqun，LIUHuazhen （DepartmentofNeurology，ShichengCountyPeople'sHospital，Shicheng3427Oo，Jiangxi，China）

Abstract：Obeieesiatetoffolccidbdiastsfcdurolalfcti withcerebralrolcaediooeyetdotalfsibalftoa withHHcywhoweretreatedinShichengCountyPeople'sHospitalfromJanuaryO1toDecember223wereselectedastheresearhoects. Accordingtotherandomumberablemetod，theyweredvidedintocontrolgroupndstudygoup，with3Opatientsineachgroup.Theotrol groupwastreateditoastatidtesudyouastreatedwitlodosefoliccdobidwitoastateapeict plasmaHcyleveldyiefutiooCAore，Sorendideefdeeactios（otesid vomitingbdoalneaedeteeossulstaltiateofratinoa that in the control group（ P<0.05） .At7daysand1 month aftertreatment，theplasmaHcylevel inthestudy groupwas lower than thatinthe control group（ P< 0.05）.The incidence of HHcy in the study group was lower than that in the control group （ P< 0.05）.After treatment，the MoCA score of the studygroup was higherthan thatof thecontrol group，whiletheNIHSSscore waslowerthanthatofthecontrol group（ P <0.05）.There was no significant difference in the incidence of adverse reactions between the two groups（ P >0.05）.Conclusion Low-dose folic acid combined with atorvastatiniseiiereaentoftitsiebalfartioomplicatedityichnduceteylce ocurrencofolaldiisdeyai

KeyWords：Folic acid;Atorvastatin; Cerebral infarction; Hyperhomocysteinemia;Neural function

脑梗死（cerebralinfarction）是一种严重的急性脑血管障碍，其高死亡率和致残率正逐年攀升，对公众健康构成重大威胁1]。（剩余6639字）