中西医结合治疗肝郁血热型多囊卵巢综合征30例临床观察
打开文本图片集
【关键词】多囊卵巢综合征；中西医结合治疗；高雄激素血症；肿瘤坏死因子 -α ；血浆D-二聚体 【中图分类号】R271.11 【文献标志码】A 【文章编号】1007-8517（2025）21-0095-06 DOI： 10.3969/j .issn.1007-8517. 2025.21. zgmzmjyyzz202521018
Abstract：ObjectiveToExplorethemechanismofactionof integrated traditional ChineseandWestemnmedicinetreatmenton polycystic ovary syndrome，as well as the effects of serum testosterone， tumor necrosis factor -α ，and plasma D -dimer. Method A totalof6Opatientsdiagnosedwithpolycysticovarysydromecombiedwithhyperandrogenism（TCMsyndromedifereniataliver depressionandblodheattype）inthe gynecologyoutpatientdepartment wererandomlydividedintoacontrol group（3Ocases）anda treatmentgroup（3Ocases）．Thecontrolgouptookoralethinylestradiolandcyproteronacetatetablets；Thetreatmentgroupreceived oral Chinese mediciegranuleswithmodifedDanzhi Xiaoyaopowderandacupuncture treatmentincombinationwiththecontrolgroup's treatment plan.Afterthreconsecutivetreatmentcourses，observethechanges intraditional Chinese medicinesyndromescores，serum testosterone， tumor necrosis factor -α ，and plasma D-dimer before and after treatment，compare the clinical efficacy of the two groups，and exploretheir mechanismsofaction.Result At theendofthetreatmentcourseand3monthsafterfollow-up，the TCM syndromescore，serumtestosterone，andtumornecrosisfactoralphainthetreatmentgroupweresignificantlylower thanthose inthe controlgroup，andtheclinicaleficacywassignificantlyigherthanthatintecontrolgroup.Therewasnostatisicallysignificant diferenceinplasmaD-dimerlevelsbeforeandaftertreatment.ConclusionTheombinationoftraditionalChineseandWestermedicinetreatmentcansignificantlyimprovetheclinicalsymptomsofpatientswithpolycysticovarysydrome，reducetumornecrosisfactor -α ，optimize theeficacyof using ethinylestradiolandcyproterone acetate tabletsalone，and be more stableandlong-lasting， which may reduce the risk of thrombosis caused by ethinylestradiol and cyproterone acetate tablets.
Key Words：Polycystic Ovary Syndrome；IntegratedTraditional Chinese and Western Medicine Treatment；Hyperandrogenemia; TumorNecrosisFactor；PlasmaD-Dimer
多囊卵巢综合征（polycysticovarysyndrome，PCOS）是在育龄期妇女中最常见的一种内分泌紊乱性疾病之一，群体发病率多在 6.00% ～10.00% ，高者可达 15%[1-2] 。（剩余8299字）
