一款猫泌尿道处方罐功效评价及其尿液代谢组学分析

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中图分类号：S856.5 文献标志码：A 文章编号：0366-6964（2025）10-5289-13

Abstract： This study aims to assess the effectiveness of a Urinary prescription canned food as an adjunctive treatment for feline lower urinary tract disease （FLUTD）.A total of twelve healthy cats were randomly assigned to two groups： the Urinary prescription canned food group （referred to as the urinary group） and a control group，with each group consisting of six cats. Throughout the feding perid，daily water intake and emotional states of the cats were monitored. Urinalysis，urine sediment examination，and measurements of magnesium （ Δ[g2+ ），oxalate （C2O42-） ， phosphate （PO43- ），and calcium（ （Ca2+ ） concentrations in urine were conducted both prior to and following the feeding regimen. Additionally，metabolomics analysis was performed on urine samples collected post-feeding. The urinary group demonstrated a higher cumulative water intake compared to the control group. Furthermore，there was a 5% increase in the proportion of positive emotional states， particularly "content"，in the urinary group relative to the control group. Post-feeding analysis revealed a significant reduction in the urinary sediment of the urinary group，including crystalline substances， casts，and urethral epithelial cell counts （ P<0.05） ， with significant differences when compared to the control group （ ⋅P<0. 05 . The concentrations of Mg2+ ， C2O42- ， PO43- ，and Ca2+ in the urine of the urinary group significantly decreased after feeding ⋅P<0. 05⋅ ），again showing significant differences from the control group （ P<0.05） 。（剩余15172字）