吲哚菁绿荧光显像技术在胆道闭锁中的应用

基金项目：广州市卫生健康科技项目（20231A011040）；广州医学院科研基金项目（2023ekky007）

Abstract：Biliaryatresia（BA）ischaracterizedbyprogresiveinflammationandfibrousobstructionofbileducts，ultimately leading tocholestaticlivercirhosis.KasaisurgeryisthestandardprocedureforthetreatmentofBA，andearlydiagnosisisakey influencingfactorfortheprognosisofBA.Indocyaninegree（ICG）isanear-infraredphotosensitivedyethatiseficientlyand selectivelyabsorbedbyepatocytesafterintravenousinjection，anditenters theintestineviabileandisexcretedwithtefecesin thefreeform，withafavorablesafetyprofile.Inaddition，ICGcanemitfluorescenceundernear-infraredlight，whichanbe capturedbycamera instrumentsandconvertedintovisualimages，andICGfluorescence imaging technologycanreflectthe intraoperativesituationinrealtimeandsignificantlyimprovethesuccessrateofthesurgicalprocedure.Thisarticlereviews the advancesintheapplicationof ICGinearlypreoperativediagnosis，intraoperativeimaging，andpostoperative liver function assessment in recent years.

KeyWords：Biliary Atresia；Indocyanine Green;Early Diagnosis

Research funding：Guangzhou Municipal Health Science and TechnologyProject（2O231A011040）；Research Fundof Guangzhou Medical University（2023ekky007）

吲哚菁绿（indocyaninegreen，ICG）是一种近红外可见的荧光三碳菁染料，1956年由美国食品和药物管理局批准使用。（剩余19683字）