中西医结合在慢加急性肝衰竭全病程管理中的特色和优势
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通信作者：，wangxianbo638@163.com（ORCID：0000-0002-3593-5741）
关键词：慢加急性肝功能衰竭；中西医结合疗法；多学科诊疗
基金项目：国家自然科学基金（82474419，82474426）；北京市卫生健康委员会-研究型病房卓越临床研究计划（BRWEP2024W102170107）；北京市医院管理中心创新梦工场经费资助（202335）
Characteristics and advantages of integrated traditional Chinese and Western medicine therapy in whole-course management of acute-on-chronic liver failure
GAO Fangyuan，FENG Ying，WANG Xianbo
Center of Integrative Medicine，Beijing Ditan Hospital，Capital Medical University，Beijing 1Ooo15，China
Corresponding author：WANG Xianbo，wangxianbo638@163.com（ORCID： 0000-0002-3593-5741）
Abstract：Acute-on-chronic liverfailure（ACLF）isacomplexclinical syndrome characterized byacute deteriorationof liver functioncaused bydiferent factorson the basisof chronic liverdisease，accompanied by liver failureand/or extrahepatic organ failure，and itoften hasa high short-term mortalityrate.With the increasing evidenceof evidence-based medicine， multipleguidelinesandconsensus statements havebeenreleased，suchas Guidelines forclinicaldiagnosisandtreatmentof acute-on-chronic liver failure intraditional Chinese medicine，Expertconsensus on thediagnosisand treatmentofacute-onchronicliverfailurewithintegratedtraditionalChineseandWesternmedicine，andGuidelines fortheintegrated traditional Chineseand Westernmedicinediagnosisandtreatmentofacute-on-chronic liverfailure，and integrated traditional Chinese and Western medicine therapies for ACLF have been constantly standardizedand perfected.This article explores the characteristicsandadvantagesof integrated traditional Chinese andWestern medicine therapyin the whole-course management of ACLF from theaspectsof early warning and prevention，treatment in theacute stage，managementof complications，andrehabilitationcare，inorder to enhancetheunderstandingof traditional Chinese and Western medicine treatment strategies among clinicians.
KeyWords：Acute-On-ChonicLiverFilure；IntegratedChineseTraditionalandWesteMedicineTherapy;Multi-DisciplinaryTeam
Research funding：NationalNaturalScienceFoundationofChina（82474419，82474426）；BeijingMunicipal HealthCommisionExcelent Clinical ResearchProgram for Research Wards（BRWEP2024W102170107）；Beijing HospitalsAuthority Innovation Studio of Young Staff Funding Support （202335）
慢加急性肝衰竭（ACLF）具有发病急骤、进展迅速、并发症多、病死率高等特点，中西医结合作为我国独特的医疗模式，在ACLF这类复杂危重症的全病程管理中展现出显著特色与优势。（剩余22797字）