基于“浊阴理论”探讨Ⅱ型心肾综合征的病机和证治

[中图分类号]R256 [文献标志码]A [文章编号]doi：10.3969/j.issn.1674-070X.2025.08.016

[Abstract]TypeIcardiorenal syndrome （CRS），aclinicallycommonchronic progresivedisease，involvesmultisysteinteractionsinitspathologicalmechanisms.Modernmedicaltreatmentsystemsprimarilyfocusoncompensatorybalanceregulationof cardiorenal functions，employing integratedapproachessuchasmaintainingcardiovascularhemodynamicstabilityoptimizing renalperfusionpressure，precisevolumemanagement，andanti-inflammatoryinterventionsfordiseasemanagement.Thisstudy basedontheacademicessnceof the"turbidyintheory"fromtheHuang DiNei Jing（Huangdi'sClassicofMedicine）and integratedwithmoderpathophysiologicalresearchadvancements，innovativelyproposesthat"turbidyindysregulation"constiutes thecorepathogenictheoryoftypeICRS.Specificaly，metabolicdysfunctionofturbidyinmanifeststhree-dimensional pathologicalfeaturesinthediseaseprocess，namely"impaiedransportationofturbidyin"，"impairedtransformationofurbid yin"，and"mpiredecetioofturbidin"ddressingtseripartitepathologicalmchanism，a"traspoatiorasfotio excretiontrinitytherapeuticstrategyisestablished：transportingturbidyintorestoreqimovement，transformingturbidyinto eliminatetoxicstagnation，andexcretingturbidyintounblockthemysteriousmansion.Atthelevelofspecifictreatment，an integratedregimenof"warmingyangtoconsolidatethefoundation，transformingphlegmandexpelingstasis，andwarmingqi topromotewatercirulation"isproposed，highlightingtheadvantagesofclasicalformulassuchasJinguiShenqiPillGualou Xiebai Baijiu Decoction， and Zhenwu Decoction in treating type II CRS.

[Keywords]typeIcardiorenalsyndrome;turbidyintheory；treatmentbasedonpaternidentification;edema;etiology nd pathogenesis

心肾综合征（cardiorenal syndrome，CRS）是指在心脏或肾脏中，一个器官的急性或慢性功能紊乱，诱发另一个器官的急性或慢性功能紊乱所导致的临床症候群；I型CRS则是指由于慢性心力衰竭（chronicheart failure，CHF）导致慢性肾衰竭（chronicrenalfailure，CRF）的临床综合征。（剩余9637字）