痰湿证证候积分联合左室射血分数对冠心病患者PCI术后 支架内再狭窄的预测价值

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[关键词」支架内再狭窄；痰湿证；经皮冠状动脉介入治疗；证候积分；左室射血分数；预测价值 [中图分类号］R541.4 [文献标志码］A [文章编号]0256-7415（2025）18-0036-06 DOI： 10.13457/j.cnki.jncm.2025.18.007

Predictive Value of Phlegm-Damp Syndrome Scores Combined with Left Ventricular Ejection Fraction for In-Stent Restenosis After PCl in Patients with Coronary Heart Disease

LIU Yu，PENG Xiongqiang Guangdong Provincial Hospital of Chinese Medicine，Guangzhou Guangdong 51O12O，China

Abstract：Objective：To investigate the predictive values of phlegm-damp syndrome scores combined with left ventricular ejection fraction（LVEF）for in-stent restenosis（ISR）after percutaneous coronary intervention（PCI）in patients with coronary heart disease．Methods：Patients with coronary heart diseasewho underwentPCI were enrolled and divided into the ISR group and the non-ISR group based on ISR occurrence.All patientsunderwent echocardiographyand were assessedfor syndrome scores according to the diagnostic criteria for phlegm-damp syndrome incoronary heart disease．General information，laboratory indices，phlegm-damp syndrome scores，and LVEF were compared between the two groups.Logistic regresion was used to analyze the risk factors of ISRafter PCI，while receiver operating characteristic （ROC）curves were used to evaluate the diagnostic efcacy of phlegm-damp syndrome scores，LVEF，and their combination for ISR．Results：It wassuggested that significant diffrences existed betweenISR and non-ISR groups in low-density lipoprotein cholesterol（LDL-C），LVEF，and phlegm-damp syndrome scores （ P<0.05 ）．Logistic regresson revealed reduced LVEF as a risk factor for ISR（OR=4.424， P =0.002），whilea phlegm-damp syndrome score ⩾6 was an independent risk factor （OR=12.875， P=0.003 ）.ROC analysis showed that thearea under the curve for predicting ISR was O.834 usingthe phlegm-damp syndrome scores alone and 0.847 when combined with LVEF.Conclusion：The combination of phlegm-damp syndrome scores and LVEF demonstrates high predictivevalue for ISRafterPCI.Thisintegratedapproachmayserveasa keyclinical indicator for ISR risk assessment，providing a reference for early clinical intervention.

Keywords： In-stent restenosis；Phlegm-damp syndrome；Percutaneous coronary intervention； Syndrome score; Leftventricular ejection fraction；Predictive value

冠状动脉粥样硬化性心脏病（简称冠心病）为临床常见的缺血性心脏病，是指冠状动脉发生狭窄或闭塞导致心肌缺血、坏死而引起的心脏病。（剩余6637字）