火针联合艾灸对脑卒中后痉挛性肌张力障碍中枢神经调控及表面肌电图的影响

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[关键词］脑卒中；痉挛性肌张力障碍；火针；艾灸；TLR4信号通路；表面肌电图 [中图分类号］R277.7 [文献标志码］A [文章编号]0256-7415（2025）01-0156-06 DOl:10.13457/j.cnki.jncm.2025.01.031

Effect of Fire Needling Combined with Moxibustion on Central Nervous Regulation and Surface Electromyography of Post-Stroke Spastic Dystonia

SHI Lin，SUN Mingming，GUO Li'na Department of Rehabilitation Medicine，Zhoukou Central Hospital，Zhoukou Henan 466Ooo，China Abstract：Objective：To observe the effct of fire needling combined with moxibustion on central nervous

regulation and surface electromyography of post-stroke spastic dystonia through toll-like receptor 4（TLR4）signaling

pathway.Methods:A total of98 patients with post-strokespastic dystonia treated in Zhoukou Central Hospital from

January 2020to May2O23 were selected anddivided into the moxibustion group and the combination group according to

random number table method，with 49 cases in each group.The two groups were given modern medical treatment；the moxibustion group was aditionally given moxibustion，and the combination group wasadditionally given fire nedling and moxibustion.Theclinical efects in the two groupswere compared.The changes in traditional Chinese medicinesyndrome scores，Clinical Spasticity Index（CSI） and Modified Ashworth Scale（MAS），Fugl-Meyer Assessment （FMA），Trunk Impairment Scale（TIS），China Stroke Scale（CSS），surface electromyographylintegrated electromyography（iEMG），rot mean square of electromyography（RMS)]，and levels of serum lipoprotein-asscited phospholipase A2（Lp-PLA2），TLR4，and serum phosphorylated α- synuclein ( α∝-syn ）were compared between the two groups before and after treatment.Results:The total efectiverateinthecombination group was beterthan that in the moxibustion group，the difference being significant ( P

Keywords:Stroke；Spastic dystonia；Fire needling；Moxibustion；TLR4 signaling pathway； Surface electromyography

脑卒中主要临床表现为神经损伤、肌肉痉挛、肌张力异常、肢体功能障碍等1-2]。（剩余12494字）