补阳还五汤联合利伐沙班治疗气虚血瘀型缺血性脑卒中后下肢深静脉血栓临床研究

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[关键词］缺血性脑卒中；下肢深静脉血栓；气虚血瘀型；补阳还五汤；D-二聚体；抗凝 [中图分类号］R259 ［文献标志码］A [文章编号]0256-7415（2025）01-0022-06 DOl:10.13457/j.cnki.jncm.2025.01.005

Clinical Study on Buyang Huanwu Decoction Combined with Rivaroxaban in Treating Deep Venous Thrombosis of Lower Limbs After lschemic Stroke of Qi Deficiency and Blood Stasis Type

JIANG Xia，CHEN Shixuan，ZHU Bin，HUANG Qiyao，CHEN Wenci，JI Jing Wenzhou Hospitalof Integrated Traditional Chineseand Western Medicine，Wenzhou Zhejiang 325Ooo,China

Abstract：Objective：To observe the clinical efect of Buyang Huanwu Decoction combined with Rivaroxaban in the treatmentof deep veinous thrombosis of lower limbs (LDVT）afterischemic strokeofqi deficiencyandblood stasis type.Methods:Atotalof118LDVTpatients hospitalizedin Wenzhou Hospitalof Integrated Traditional Chineseand Western Medicine from July 2O22 to June 2023 after ischemic strokewith qi deficiencyand blood stasis type were randomly divided into control group and observation group with 59 cases in each group according to envelope method. Onecase in thecontrol group was excluded forfailto takeChinese medicine orally follwdoctor'sadvice，andone case in the observation group was excluded for early discharge from the hospital，and finally，58 cases in each group completed the study.Both groups received conventional treatment.The control group was treated with Rivaroxaban on the basis of conventional treatment，and the observation group was treated with Buyang Huanwu Decoction combined with Rivaroxabanonthe basisofconventional treatment，Both groups were treated for14days.The clinical efficacy, tradional Chinese medicine（TCM）syndrome score，Stroke Scale（NIHSS）score，Barthel Index（Barthel） score and Villta score，blood cloting index [D-Dimer（D-D），homocysteine（Hcy），fibrinogen（FIB），prothrombin time（PT），activated partial thromboplastin time（APTT），thrombin time（TT)]level of the two groups was compared.Results:After 14 days of treatment，the total efective rate of the observation group was 93.10%（54/58）, higher than that of the control group 82.76 % (48/58）( P

Keywords:Ischemic stroke；Deep venous thrombosis of lower limbs；Qi deficiency and blood stasis type; Buyang Huanwu Decoction；D-Dimer；Anticoagulation

下肢深静脉血栓(LDVT)是缺血性脑卒中常见并发症，发病率较高，由于本病起病隐匿，早期无临床症状和体征，识别较为困难，对缺血性脑卒中后LDVT早期预防、抗凝治疗具有重要的临床意义。（剩余12426字）