DSA引导下经皮穿刺微球囊压迫术治疗原发性三叉神经痛的临床疗效

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[Abstract]Objective:Toevaluatetheclinical eficacyof percutaneousmicrobalooncompresson(PMC)guidedbyDSA in thetreatment ofprimary trigeminal neuralgia. Methods : 30 patients with primary trigeminal neuralgia were treated withstandardized PMC.The Brisman efficacy evaluation criteria,visual analogue scale (VAS) score,Barrow Neurologic Institute(BNI)painscalegrading,postoperativecomplications,andrecurrencewereobservedatdiferenttimesaftersurgery. Results:The total effctive rate of PMC was 96.7%(29/30),among them,19 cases were cured( 63.3% ),8 cases were significantlyimproved(26.7%),2 cases were effective (6.7%),and1 case was ineffective( 3.3% ).Comparedto before PMC,in 1day,monthand6monthsafterPMC,theVAscoressignificantlydcreased,Bpainscalegradingsignificantlyiroed, and the diferences were statistically significant (both P<0.05 ).The incidence of postoperative sensory abnormalities and masticatory muscle weaknesswere relatively high,and significantly decreasedat 6 months after PMC(both P<0.05 ).After 6monthsoffolow-up,there wereatotalof2casesofrecurrenceandnodeaths.Conclusions:PMCguidedbyDSAhasa goodtherapeuticefectontrigeminal neuralgia.Complicationscanbegraduallyrelieved,therecurrencerateis low,and it has good safety and efficacy.
[Keywords]Percutaneousmicrobalooncompresion;Angiogaphydigitalsubtraction;Trigeminalneuralgia;Therapeticefect
三叉神经痛是一种临床常见病、多发病,多为单侧头面部阵发性剧烈疼痛,多发于中老年人,严重影响患者生活质量;临床常用卡马西平和加巴喷丁等药物治疗,具有一定止疼效果,但不良反应较大,长期应用易产生耐受性[]。(剩余5000字)