多模态超声预测乳腺癌腋窝淋巴结转移的临床价值

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[Abstract]Objective：Toevaluatethepredictivevalueof multimodalultrasoundforaxillrylymphnodemetastasis（ALNM） inbreastcancer.Methods：Theultrasoundandclinicaldataof92patientswithbreastcancerwereretrospectivelycolected. All patintsreceivedgrayscaleultrasoundcolorDopplerultrasoundandcontrast-enhancedultrasoundpreoperativelyAccodngto the postoperativepathologicalresults，the patientsweredividedinto ALNMgroup（3Ocases）andnon-ALNM group（62cases）. Thegrayscaleultrasound，colorDopplerultrasound，contrast-enhancedultrasoundfeaturesbetweenthetwogroupswere compared，andlogisticegressionanalysiswasperformedtodeterminetheindependentpredictorsofALMinbreastcancer. ROCcurvesweredrawn toevaluatethediagnosticperformanceofeachpredictor.Results：Thediferencesinthebloodflow grade，enhancementdirection，adialenhancementatthelesionmarginandfeedingeselswerestatisticallysignificantbetween the two groups （all P<0.05 ）.Multivariate logistic regression analysis showed that blood flow grading ofII-Ⅲ ，radial enhancementatthelesionmargin，andfeedingveselsweretheindependentpredictivefactorsforALNMinbreastcancer. ROCcurveanalysisshowedthattheAUCsofaboveindicatorspredicting theALNMwere0.697，0.603，0.665respectively， while the combined AUC was O.837，higher than the single indicator（all P<0.05 ）.Conclusions：The blood flow grading of （20 |-|| ，radialenhancementatthe lesion margin，and feeding veselsareindependent predictive factors for ALNMin breast cancer，thecombinationofthethreeindicatorshasahigherpredictivevalue，whichcanprovidemorereferableinformationfor clinical treatment and prognosis evaluation.

[Key words] Breast neoplasms;Axillary;Lymph node metastasis;Ultrasonography

乳腺癌是女性最常见的癌症，也是全球女性因癌症死亡的第二大病因[1]。（剩余7627字）