静脉持续泵入替罗非班在标准支架辅助颅内动脉瘤栓塞中的应用

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Application of Intravenous Continuous Pumping of Tirofiban in Standard Stent-Assisted Intracranial Aneurysm Embolization

QIUJun* GAO Feng HUI Peng （Shandong Shanxian Dongda Hospital Co.， Ltd.）

Abstract：Objective：To investigatetheeffect of intravenouscontinuous pumpingof tirofibancombinedwith standard stent implantation in patients with intracranialaneurysm.Methods： From January 202l to January 2024， 80 patients with intracranial aneurysm who underwent standard stent implantation in Shandong Shanxian Dongda Hospital were selected，andrandomlydivided intotwo groups with 40 patients in each group.Thecontrol group was treated with conventional antiplatelet drugs， and the observation group was treated with tirofiban based onthe control group. Immediate embolization effect，coagulation function， perioperative complications and postoperative adverse reactions were comparedbetween the two groups.Results：After treatmentthe immediateembolization effect， PLTand APTT of the observation group were higherthan those of thecontrol group，andthe incidence ofperioperative complications and postoperative adverse reactions of the observation group were lower than those of the control group （P<0.05） ， Conclusion： Intravenous continuous pumping of Tirofiban combined with standard stent implantation has a good efectin patientswith intracranialaneurysm，which can improve the coagulation function of patients and reduce the incidence of perioperative complications and postoperative adverse reactions.

Keywords：travenuscontiuouspumpingTirofbanstandardstentimplantationitracranialaneurysmembolizion

0 引言

颅内动脉瘤（instracranialaneurysm）属于常见的脑血管疾病，其特点是颅内动脉管腔局部的异常扩张，严重影响患者的生活质量。（剩余4263字）