功能小气道、肺血管CT定量分析对COPD早期诊断的临床价值

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中图分类号：R445 文献标识码：A

DOI：10.3969/j.issn.1006-1959.2025.15.031 文章编号：1006-1959（2025）15-0141-04

Clinical Value of CT Quantitative Analysis of Functional Small Airways andPulmonaryVesselsintheEarlyDiagnosisofCOPD

ZHU Ye

（Departmentof ClinicalLaboratory，Ruizhou Hospital，Gao'an33O8Oo，Jiangxi，China）

Abstract：ObectieTinvestigatethlicalvalueoffunctioalalliaydulmonaryascularCuantativenalysisinly diagnosisofCOMethodsFromMay1toApril224，58patientswithsuspectedCOhoeretreatedinuzouHospitalfGaoaCity and58healhbetsitpdeeseahtsndedineoolo respectively.Theparameterresponseiagram（R）andpumonaryvascularparametersoftheoleungerequantitativelymeasuredinoth groups.The PRM parameters [emphysema volume （PRMV kmphysem ），functional small airwayvolume （PRMV ，normal partial lung volume （PRMV Noma ） and its volume percentage （%）- and pulmonaryvascularparameters[numberofpulmonaryvessels（N），numberofsmall vesels withcross-sectional area <5mm2（N-（SA<5））] at6，9，12，15，18，21and24mmfromthe wholelung tothepleura werecomparedbetweenthetwogroups.Thediagnostic valueofPRMparametersasculararameesndtheirombinationforarlyOPwasanalydResultsTelevelsofRMV （2 PRMVEnphysema% and PRMV fsAD% inthestudygroup were higherthan those in thecontrol group，whilethelevelsof PRMV Nomal and PRMV Nomal% were lower than those in thecontrol group（ P<0.05） .When the wholelung was6mm and9mm from the pleura，the levelsof Nand N-∞a< in the study group were lower than those in the control group （ P< 0.05）.When the whole lung was12，15，18，21and 24 mm away from the pleura，the levelsof Nand N-CsA< inthe study group were higher than thosein the control group（ P<0.05 ）.Thesensitivity，specificity，accuracy，positivepredictive valueand negative preditivealueofantiativenalysisoffnctioalsallaiaydpumoarysulaCiheiagosisfOereighettoef PRM parameters and vascular parameters alone （ P<0.05 .Conclusion CT quantitative analysis offunctional small airways and pulmonary vessels has ahighclincalueiosisOtegiaiaiaeeofcaall pulmonary vessels in COPD patients，and provideobjective basis for individualized evaluationand treatment.

KeyWords：Functional small airway; Pulmonary vascular CT; Quantitative analysis; COPD;Earlydiagnosis

全球范围内，慢性阻塞性肺疾病（COPD）的流行趋势严峻，其特征性的气流受限问题日益引起关注，已跃升为全球死亡率排名第三的重大公共卫生问题。（剩余5789字）