DPOAE及EcochG在听力正常耳鸣病人中的应用价值

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[关键词]耳鸣；耳声发射，自发性；测听法，诱发反应[中图分类号]R764.45 ［文献标志码］A [文章编号] 2096-5532（2025）05-0763-04doi：10.11712/jms.2096-5532.2025.61.162 [开放科学（资源服务）标识码（OSID）][网络出版]https：//link.cnki.net/urlid/37.1517.R.20251118.1709.002； 2025-11-1916：51：31

Applicationvalue of distortionproduct otoacoustic emissonandelectrocochleographyintinitus patients withnormal hearingLU Zhenjun，JIN Shuxiang，GE Ruifeng，XIN Ying， WANG Yi（Department of Otolaryngology Head and Neck Surgery，The Affiliated Hospital of Qingdao University，Qingdao 266ooo，China）

[Abstract]ObjectiveToinvestigate thefeatures ofdistortion product otoacoustic emision（DPOAE）andelectrocochleog raphy（EcochG）intinntus patients withnormalhearing，andtoexploretheiraplicationvalueintinitusassssment.Methods Atotalof34tinnituspatients（38ears）withnormalhearing wereenroledasobservation group，and25healthycontrols（50ears） with normal hearingand theabsence of tinnitus wereenrolledas control group.DPOAEand EcochG testing were performed for both groups，andthe two groups were comparedin terms of DPOAE passrate and signal-to-noiseratio（SNR）at each frequency point，as well as - summating potential （-SP） ，compound action potential（AP）of auditory nerve，and -SP/AP ratio on EcochG，while thediference in DPOAEresponse amplitude was compared between acute and chronic tinnitus.ResultsCompared withthecontrolgroup，theobservationgrouphadasignificantlylowerdetectionrateofDPOAEat0.5o，O.75，1.0o，2.00， and 3.00kHz frequency points ⟨χ2=3.63-37.36，P<0.05⟩ and a significantly lower SNR of DPOAE at 0.50-4.00kHz frequency points （ t=-9.85 to -6.42，P<0.01⟩ . Compared with the control group，the observation group had a significantly lower AP amplitude （t=-8.01，P<0.01） and a significantly higher -SP/AP ratio （t=13.00，P<0.01） ，while there was no significant difference in -SP amplitude between the two groups （ P>0.05 .There was only a significant difference in DPOAE response amplitude at 1.50kHz frequency point between the patients with acute tinnitus and those with chronic tinnitus （t=2.34，P<0.05） .ConclusionTinitus patients with normalhearing mayhaveearlydamageofthecochlea，whichisnotlimitedtoaspecificfrequency，and theeffectofdurationoftinnitusoncochlearfunction mightnotbeadeterminingfactor.DPOAEandEcochGcanbeusedasobjective methods for the diagnosis of tinnitus，showing an important valuein assessing the early damage of the cochlea.

[Key words] tinnitus；otoacoustic emissons， spontaneous；audiometry，evoked response

耳鸣包括主观耳鸣和客观耳鸣，主观性耳鸣是指在没有外界相关声源及电（磁）刺激情况下，病人主观感受到的声音，临床上较为多见[1-4]。（剩余6919字）